Literature DB >> 18408978

Launois-Bensaude Syndrome: an unusual localization of obesity disease.

Giovanni Verna1, Nicola Kefalas, Filippo Boriani, Salvatore Carlucci, Ingrid Choc, Maria Alessandra Bocchiotti.   

Abstract

BACKGROUND: Launois-Bensaude syndrome is a rare pathology consisting of adipose masses symmetrically distributed mainly in the superior part of the body. Men are especially affected between age of 30 and 60 as well as chronic alcohol abusers. Etiopathogenesis is attributable to mutations or deletions of mitochondrial DNA, and alcohol is a possible cofactor.
METHODS: The current treatment of the disease is described based on the authors' experience. Four cases treated in our department are retrospectively reviewed regarding comorbidities and type of surgery performed.
RESULTS: A relevant and long-lasting reduction of fat bulges has been obtained in all cases with no major complications except for a mild anemia.
CONCLUSION: Launois-Bensaude syndrome causes a functional rather than esthetic concern due to the peculiar localization of fat bulges. Currently, the only effective therapy is surgery, through lipectomy or liposuction of adipose bulges.

Entities:  

Mesh:

Year:  2008        PMID: 18408978     DOI: 10.1007/s11695-008-9502-2

Source DB:  PubMed          Journal:  Obes Surg        ISSN: 0960-8923            Impact factor:   4.129


  34 in total

1.  Multiple symmetrical lipomatosis (Madelung's disease).

Authors:  Y A Gabriel; D K Chew; R V Wedderburn
Journal:  Surgery       Date:  2001-01       Impact factor: 3.982

2.  Tumescent liposuction in a patient with Launois-Bensaude syndrome and severe hepatopathy.

Authors:  Alfred Grassegger; Rudolf Häussler; Franz Schmalzl
Journal:  Dermatol Surg       Date:  2007-08       Impact factor: 3.398

Review 3.  The plastic surgeon in the treatment of obesity.

Authors:  Giacomo Datta; Luca Cravero; Andrea Margara; Filippo Boriani; Maria Alessandra Bocchiotti; Nicola Kefalas
Journal:  Obes Surg       Date:  2006-01       Impact factor: 4.129

4.  Symmetric lipomatoses in female patients.

Authors:  P G Stavropoulos; C C Zouboulis; C Trautmann; C E Orfanos
Journal:  Dermatology       Date:  1997       Impact factor: 5.366

5.  Benign symmetrical lipomatosis (Madelung's disease).

Authors:  M A Shugar; J P Gavron
Journal:  Otolaryngol Head Neck Surg       Date:  1985-02       Impact factor: 3.497

6.  ["Fatty neck." Symmetrical lipomatosis with Madelung's symptom (author's transl)].

Authors:  R Jaske; H Holzer; H Popper
Journal:  Laryngol Rhinol Otol (Stuttg)       Date:  1980-11

7.  Computed tomography of deep fat masses in multiple symmetrical lipomatosis.

Authors:  G Enzi; P R Biondetti; D Fiore; F Mazzoleni
Journal:  Radiology       Date:  1982-07       Impact factor: 11.105

8.  Mitochondrial dysfunction in multiple symmetrical lipomatosis.

Authors:  S F Berkovic; F Andermann; E A Shoubridge; S Carpenter; Y Robitaille; E Andermann; C Melmed; G Karpati
Journal:  Ann Neurol       Date:  1991-05       Impact factor: 10.422

9.  Differential clinical expression of multiple symmetric lipomatosis in men and women.

Authors:  L Busetto; D Sträter; G Enzi; A Coin; G Sergi; E M Inelmen; S Pigozzo
Journal:  Int J Obes Relat Metab Disord       Date:  2003-11

10.  Coupling between the beta-adrenergic receptor and the adenylate cyclase--pathophysiological implications.

Authors:  C Wesslau
Journal:  Acta Med Scand Suppl       Date:  1983
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  3 in total

1.  Osteoporosis, weight gain and atypical fat accumulations - a typical feature not only for Cushing's, but also Madelung's disease: A case report.

Authors:  Claudia Friedl; Eva Sampl; Eva-Christina Prandl; Doris Wagner; Jutta C Piswanger-Soelkner; Alexander R Rosenkranz; Astrid Fahrleitner-Pammer
Journal:  Wien Klin Wochenschr       Date:  2011-09-15       Impact factor: 1.704

2.  The use of high tumescent power assisted liposuction in the treatment of Madelung's collar.

Authors:  Henryk Witmanowski; Łukasz Banasiak; Grzegorz Kierzynka; Jarosław Markowicz; Jerzy Kolasiński; Katarzyna Błochowiak; Paweł Szychta
Journal:  Postepy Dermatol Alergol       Date:  2017-08-02       Impact factor: 1.837

Review 3.  Madelung's Disease: Lipectomy or Liposuction?

Authors:  Chun-Ye Chen; Qing-Qing Fang; Xiao-Feng Wang; Min-Xia Zhang; Wan-Yi Zhao; Bang-Hui Shi; Li-Hong Wu; Li-Yun Zhang; Wei-Qiang Tan
Journal:  Biomed Res Int       Date:  2018-02-21       Impact factor: 3.411

  3 in total

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