Literature DB >> 18408879

Association between quantitative measures of skin color and plasma 25-hydroxyvitamin D.

J E P Rockell1, C M Skeaff, S M Williams, T J Green.   

Abstract

UNLABELLED: We examined the relationship between vitamin D and skin color measured by reflectance colorimetry at an exposed and un-exposed site in 321 people. Exposed but not unexposed skin color was associated with better vitamin D status. Sun-exposure was more important than natural skin color in determining vitamin D status in our population.
INTRODUCTION: Vitamin D is obtained through UV synthesis in the skin where melanin limits its synthesis. Ethnicity is often used as a proxy for skin color, but skin color varies considerably. The relation between quantitative measures of skin color and plasma 25-hydroxyvitamin D (25OHD) concentration has not been well described.
METHODS: The aim of this study was to determine the association between constitutive (natural) and sun-induced skin color and 25OHD in a group of Pacific People (n = 87) and Europeans (n = 255) living in NZ (46 degrees S) in summer. Plasma 25OHD was determined and sun-induced (outer fore-arm) and constitutive (upper inner-arm) measured by reflectance colorimetry.
RESULTS: Mean (SD) 25OHD was significantly higher in Europeans than Pacific People, 88 (31) nmol/L vs. 75 (34) nmol/L, respectively. Based on constitutive skin color, 35% of participants were very light, 45% light, 16% intermediate, 4% tanned, and 0% brown or dark. Skin color at the forearm but not constitutive skin color was a significant predictor of 25OHD. Each 10 degrees lower skin color value at the forearm (more tanning) was associated with a 5 nmol/L higher 25OHD (P < 0.001).
CONCLUSIONS: Tanning but not natural skin color was an important determinant of 25OHD. Further study is needed in a population with a higher proportion of darker skin people.

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Year:  2008        PMID: 18408879     DOI: 10.1007/s00198-008-0620-4

Source DB:  PubMed          Journal:  Osteoporos Int        ISSN: 0937-941X            Impact factor:   4.507


  16 in total

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