| Literature DB >> 18408848 |
Ricardo Evangelista Marrocos de Aragão1, Cristina Muccioli, Ieda Maria Alexandre Barrreira, Daniel Canamary Silveira Ribeiro, Cristiane Nobrega Gularte Timóteo.
Abstract
Cryptococcal meningitis is caused by the yeast Cryptococcus neoformans. Two varieties are recognized: var. gattii and var. neoformans. It is usually associated with immunosuppressive states, particularly HIV infection. Cryptococcal infection of the central nervous system is uncommon in immunocompetent children and difficult to diagnose. Ocular complications are common. Optic disc swelling was found in 33%. The following report describes a case of meningitis caused by C. neoformans var. gattii in an 8 year-old immunocompetent child who developed optic atrophy. The patient was treated with amphotericin B associated with corticosteroids. Possible therapeutic strategies aimed at reducing visual loss in cryptococcal meningitis have great importance to avoid this important morbidity.Entities:
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Year: 2008 PMID: 18408848 DOI: 10.1590/s0004-27492008000100021
Source DB: PubMed Journal: Arq Bras Oftalmol ISSN: 0004-2749 Impact factor: 0.872