| Literature DB >> 18407645 |
Kuo-Wei Lin1, Chi-Hui Tsai, I-Lin Hsieh, Tu-Hsin Yan.
Abstract
The direct coupling of a variety of amides with CH2 Cl2 or CD2 Cl2 promoted by TiCl 4/Mg/THF provides an extremely simple, practical, selective, and efficient approach for the construction of methyl ketones. The efficiency and practicability of this chemistry is illustrated by the very simple synthesis of deuterated methyl ketones.Entities:
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Year: 2008 PMID： 18407645 DOI： 10.1021/ol8004326
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005