Literature DB >> 18407189

Islet cell growth and the growth factors involved.

S Bonner-Weir1, F E Smith.   

Abstract

Throughout development, growth and aging, the mass of the pancreatic islets, in particular the insulin producing beta cell, increases to meet the functional demand and maintain euglycemia. Islet growth occurs by two pathways: (a) the expansion by replication of preexisting beta cells and (b) the formation of new islets (neogenesis) by proliferation and subsequent differentiation of pancreatic ductal epithelium. Some of the factors involved in these pathways of islet growth have been defined.

Entities:  

Year:  1994        PMID： 18407189     DOI： 10.1016/1043-2760(94)90003-5

Source DB:  PubMed          Journal:  Trends Endocrinol Metab        ISSN： 1043-2760            Impact factor:   12.015


  13 in total

1.  Evidence for a circulating islet cell growth factor in insulin-resistant states.

Authors:  S N Flier; R N Kulkarni; C R Kahn
Journal:  Proc Natl Acad Sci U S A       Date:  2001-06-12       Impact factor: 11.205

Review 2.  Insulin-like growth factor-I regulation of immune function: a potential therapeutic target in autoimmune diseases?

Authors:  Terry J Smith
Journal:  Pharmacol Rev       Date:  2010-04-14       Impact factor: 25.468

3.  Glucose metabolism-related protein 1 (GMRP1) regulates pancreatic beta cell proliferation and apoptosis via activation of Akt signalling pathway in rats and mice.

Authors:  X Wang; Y Liu; Z Yang; Z Zhang; W Zhou; Z Ye; W Zhang; S Zhang; Z Yang; X Feng; F Chen; R Hu
Journal:  Diabetologia       Date:  2011-01-26       Impact factor: 10.122

4.  Beta cell expression of IGF-I leads to recovery from type 1 diabetes.

Authors:  Mónica George; Eduard Ayuso; Alba Casellas; Cristina Costa; Jean Christophe Devedjian; Fatima Bosch
Journal:  J Clin Invest       Date:  2002-05       Impact factor: 14.808

5.  Role of FGF1, FGF2 and FGF7 in the development of the pancreas from control and streptozotocin-treated hamsters.

Authors:  M Inchovska; V Ogneva; Y Martinova
Journal:  Cell Prolif       Date:  2006-12       Impact factor: 6.831

Review 6.  Nutrient toxicity in pancreatic beta-cell dysfunction.

Authors:  E Roche; I Maestre; F Martín; E Fuentes; J Casero; J A Reig; B Soria
Journal:  J Physiol Biochem       Date:  2000-06       Impact factor: 4.158

7.  Glucose effects on beta-cell growth and survival require activation of insulin receptors and insulin receptor substrate 2.

Authors:  Anke Assmann; Kohjiro Ueki; Jonathon N Winnay; Takahashi Kadowaki; Rohit N Kulkarni
Journal:  Mol Cell Biol       Date:  2009-03-09       Impact factor: 4.272

8.  Loss of GLUT2 glucose transporter expression in pancreatic beta cells from diabetic Chinese hamsters.

Authors:  A Jörns; M Tiedge; E Sickel; S Lenzen
Journal:  Virchows Arch       Date:  1996-06       Impact factor: 4.064

9.  Insulin-like growth factor-II gene expression in a rat insulin-producing beta-cell line (INS-1) is regulated by glucose.

Authors:  M Asfari; W De; M Nöel; P E Holthuizen; P Czernichow
Journal:  Diabetologia       Date:  1995-08       Impact factor: 10.122

10.  Insulin-like growth factor and fibroblast growth factor expression profiles in growth-restricted fetal sheep pancreas.

Authors:  Xiaochuan Chen; Paul J Rozance; William W Hay; Sean W Limesand
Journal:  Exp Biol Med (Maywood)       Date:  2012-05-10
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