| Literature DB >> 18406334 |
Moustapha Kassem1, Basem M Abdallah, Hamid Saeed.
Abstract
The osteoblast is the bone forming cell and is derived from mesenchymal stem cells (MSC) present among the bone marrow stroma. MSC are capable of multi-lineage differentiation into mesoderm-type cells such as osteoblasts and adipocytes. Understanding the mechanisms underlying osteoblast differentiation from MSC is a central topic in bone biology that can provide insight into mechanisms of bone maintenance and also novel pharmacological targets to increase osteoblast differentiation and consequently bone formation.Entities:
Mesh:
Year: 2008 PMID: 18406334 DOI: 10.1016/j.abb.2008.03.028
Source DB: PubMed Journal: Arch Biochem Biophys ISSN: 0003-9861 Impact factor: 4.013