Literature DB >> 18404333

Potential anthelmintic: D-psicose inhibits motility, growth and reproductive maturity of L1 larvae of Caenorhabditis elegans.

Masashi Sato1, Hiroyuki Kurose, Toru Yamasaki, Ken Izumori.   

Abstract

No anthelmintic sugars have yet been identified. Eight ketohexose stereoisomers (D- and L-forms of psicose, fructose, tagatose and sorbose), along with D-galactose and D-glucose, were examined for potency against L1 stage Caenorhabditis elegans fed Escherichia coli. Of the sugars, D-psicose specifically inhibited the motility, growth and reproductive maturity of the L1 stage. D-Psicose probably interferes with the nematode nutrition. The present results suggest that D-psicose, one of the rare sugars, is a potential anthelmintic.

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Year:  2008        PMID： 18404333     DOI： 10.1007/s11418-007-0220-1

Source DB:  PubMed          Journal:  J Nat Med        ISSN： 1340-3443            Impact factor:   2.343


  9 in total

1.  Studies on crude drugs effective on visceral larva migrans. I. Identification of larvicidal principles in betel nuts.

Authors:  F Kiuchi; N Miyashita; Y Tsuda; K Kondo; H Yoshimura
Journal:  Chem Pharm Bull (Tokyo)       Date:  1987-07       Impact factor: 1.645

2.  Studies on crude drugs effective on visceral larva migrans. III. The bursting activity of tannins on dog roundworm larva.

Authors:  F Kiuchi; Y Tsuda; K Kondo; H Yoshimura; I Nishioka; G Nonaka
Journal:  Chem Pharm Bull (Tokyo)       Date:  1988-05       Impact factor: 1.645

3.  Effects of oral D-tagatose, a stereoisomer of D-fructose, on liver metabolism in man as examined by 31P-magnetic resonance spectroscopy.

Authors:  B Buemann; H Gesmar; A Astrup; B Quistorff
Journal:  Metabolism       Date:  2000-10       Impact factor: 8.694

4.  Mass production of D-psicose from d-fructose by a continuous bioreactor system using immobilized D-tagatose 3-epimerase.

Authors:  K Takeshita; A Suga; G Takada; K Izumori
Journal:  J Biosci Bioeng       Date:  2000       Impact factor: 2.894

5.  Mechanism of hemolysis of canine erythrocytes induced by L-sorbose.

Authors:  I Goto; M Inaba; T Shimizu; Y Maede
Journal:  Am J Vet Res       Date:  1994-02       Impact factor: 1.156

6.  Regulation of body size and behavioral state of C. elegans by sensory perception and the EGL-4 cGMP-dependent protein kinase.

Authors:  Manabi Fujiwara; Piali Sengupta; Steven L McIntire
Journal:  Neuron       Date:  2002-12-19       Impact factor: 17.173

7.  Hepatic metabolism during constant infusion of fructose; comparative studies with 31P-magnetic resonance spectroscopy in man and rats.

Authors:  S Masson; O Henriksen; A Stengaard; C Thomsen; B Quistorff
Journal:  Biochim Biophys Acta       Date:  1994-03-02

8.  Potential anthelmintics: polyphenols from the tea plant Camellia sinensis L. are lethally toxic to Caenorhabditis elegans.

Authors:  Daisuke Mukai; Noriko Matsuda; Yu Yoshioka; Masashi Sato; Toru Yamasaki
Journal:  J Nat Med       Date:  2008-01-18       Impact factor: 2.343

9.  Toxicity of tannins towards the free-living nematode Caenorhabditis elegans and the brine shrimp Artemia salina.

Authors:  Toru Yamasaki; Masashi Sato; Tomoaki Mori; Ahmed S A Mohamed; Kyoko Fujii; Junko Tsukioka
Journal:  J Nat Toxins       Date:  2002-08
  9 in total
  2 in total

1.  D-allose and D-psicose reinforce the action of metronidazole on trichomonad.

Authors:  Masakazu Harada; Emi Kondo; Hiromi Hayashi; Chigusa Suezawa; Setsuo Suguri; Meiji Arai
Journal:  Parasitol Res       Date:  2011-09-29       Impact factor: 2.289

Review 2.  Enzymes for the biocatalytic production of rare sugars.

Authors:  Koen Beerens; Tom Desmet; Wim Soetaert
Journal:  J Ind Microbiol Biotechnol       Date:  2012-02-14       Impact factor: 3.346
  2 in total

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