Literature DB >> 1840291

Epithelial cell plasticity in neoplasia.

J Jouanneau1, G C Tucker, B Boyer, A M Vallés, J P Thiery.   

Abstract

Tumor metastasis is associated with an increase in the plasticity of malignant cells, a phenomenon that is characterized by changes in cell morphology and a decrease in intercellular cohesiveness. The plasticity of cells is correlated with their motility. Therefore, factors that enhance plasticity promote the migration of malignant cells from a primary tumor. Several cytokines that induce the dissociation and dispersal of malignant cells have now been described. By inhibiting the activity of motogenic cytokines, it may be possible to design effective strategies for the treatment of patients with metastatic cancer.

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Year:  1991        PMID： 1840291

Source DB:  PubMed          Journal:  Cancer Cells        ISSN： 1042-2196


  8 in total

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Journal:  J Math Biol       Date:  2012-05-08       Impact factor: 2.259

Review 2.  Invasion promoter versus invasion suppressor molecules: the paradigm of E-cadherin.

Authors:  M Mareel; M Bracke; F Van Roy
Journal:  Mol Biol Rep       Date:  1994-01       Impact factor: 2.316

3.  Morphotypic plasticity in vitro and in nude mice of epithelial mouse mammary cells (NMuMG) displaying an epithelioid (e) or a fibroblastic (f) morphotype in culture.

Authors:  C Van den Broecke; K Vleminckx; G De Bruyne; L Van Hoorde; L Vakaet; F Van Roy; M Mareel
Journal:  Clin Exp Metastasis       Date:  1996-05       Impact factor: 5.150

4.  Intrinsic Differences in Spatiotemporal Organization and Stromal Cell Interactions Between Isogenic Lung Cancer Cells of Epithelial and Mesenchymal Phenotypes Revealed by High-Dimensional Single-Cell Analysis of Heterotypic 3D Spheroid Models.

Authors:  Maria L Lotsberg; Gro V Røsland; Austin J Rayford; Sissel E Dyrstad; Camilla T Ekanger; Ning Lu; Kirstine Frantz; Linda E B Stuhr; Henrik J Ditzel; Jean Paul Thiery; Lars A Akslen; James B Lorens; Agnete S T Engelsen
Journal:  Front Oncol       Date:  2022-04-22       Impact factor: 5.738

5.  E-cadherin expression in colorectal cancer. An immunocytochemical and in situ hybridization study.

Authors:  S Dorudi; J P Sheffield; R Poulsom; J M Northover; I R Hart
Journal:  Am J Pathol       Date:  1993-04       Impact factor: 4.307

Review 6.  Epithelial carcinogenesis in the mouse: correlating the genetics and the biology.

Authors:  S Frame; R Crombie; J Liddell; D Stuart; S Linardopoulos; H Nagase; G Portella; K Brown; A Street; R Akhurst; A Balmain
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1998-06-29       Impact factor: 6.237

7.  The conversion of mouse skin squamous cell carcinomas to spindle cell carcinomas is a recessive event.

Authors:  A B Stoler; F Stenback; A Balmain
Journal:  J Cell Biol       Date:  1993-09       Impact factor: 10.539

8.  Prognostic value of poorly differentiated clusters in invasive breast cancer.

Authors:  Ying Sun; Fenli Liang; Wei Cao; Kai Wang; Jianjun He; Hongyan Wang; Yili Wang
Journal:  World J Surg Oncol       Date:  2014-10-12       Impact factor: 2.754
  8 in total

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