Literature DB >> 18402605

Microbial complexes in supragingival plaque.

A D Haffajee1, S S Socransky, M R Patel, X Song.   

Abstract

BACKGROUND/AIMS: To examine microbial communities in supragingival biofilm samples.
METHODS: Supragingival plaque samples were taken from 187 subjects at baseline (n = 4745). Fifty-five subjects provided supragingival plaque samples at 1-7 days after professional tooth cleaning (n = 1456); 93 subjects provided 8044 samples between 3 and 24 months post-therapy. All samples were individually analyzed for their content of 40 bacterial species using checkerboard DNA-DNA hybridization. Microbial associations among species were sought using cluster analysis and community ordination techniques for the three groups separately.
RESULTS: Six complexes were formed for the baseline samples. Similar complexes were formed for the samples taken 3-24 months post-therapy. However, distinct changes were observed in microbial communities in samples taken during the 7 days of plaque redevelopment. The complexes related to clinical parameters of periodontal disease.
CONCLUSION: There were specific microbial complexes in supragingival plaque that were similar to those found in subgingival plaque samples with a few minor differences. The relation of previously unclustered taxa to the complexes was also described.

Entities:  

Mesh:

Year:  2008        PMID: 18402605     DOI: 10.1111/j.1399-302X.2007.00411.x

Source DB:  PubMed          Journal:  Oral Microbiol Immunol        ISSN: 0902-0055


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