| Literature DB >> 1840147 |
K R Rasmussen1, E G Martin, M J Arrowood, M C Healey.
Abstract
Treatment of rats immunosuppressed with dexamethasone and inoculated with Cryptosporidium parvum oocysts were treated with dehydroepiandrosterone. A significant reduction in cryptosporidial activity was observed as determined by oocyst shedding and colonization of host tissue by parasites. Dexamethasone treatment alone resulted in decreases in T-, B- and natural killer (NK) cell responses and antibody production that, with the exception of NK-cell activity, were all reversed after administration of dehydroepiandrosterone.Entities:
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Year: 1991 PMID： 1840147
Source DB: PubMed Journal: J Protozool ISSN： 0022-3921