Literature DB >> 18401327

[Macular edema from various etiologies].

P-L Cornut1, C Français-Maury, M Mauget-Faÿsse.   

Abstract

Macular edema typically occurs as the final ocular manifestation of many intraocular or systemic diseases with fluid collection within the macular layers due to the breakdown of the blood-retinal barrier. This could be chemically mediated by VEGF, because increased VEGF has been shown to increase blood-retinal barrier permeability, or mechanically induced by vitreomacular traction causing hemodynamic or retinal pigment epithelium pump disturbances. This article reviews the different clinical entities of macular edema, focusing on their physiopathological concepts and on the current therapeutic strategies for their management.

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Year:  2008        PMID: 18401327     DOI: 10.1016/s0181-5512(08)70361-9

Source DB:  PubMed          Journal:  J Fr Ophtalmol        ISSN: 0181-5512            Impact factor:   0.818


  1 in total

1.  Intravitreal vascular endothelial growth factor.

Authors:  Thomas Bertelmann; Stephan Schulze; Reka Bölöni; Walter Sekundo; Sebastian Irle; Thomas Stief; Stefan Mennel
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2014-02-04       Impact factor: 3.117

  1 in total

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