Literature DB >> 18401081

How can we achieve success in understanding the aetiology of AIS?

Keith Bagnall1.   

Abstract

A cure to prevent scoliosis from developing does not seem to be available in the near future. Primarily this is because of a lack of understanding of the aetiology of this devastating disease or cosmetic deformity. While extensive research has been performed in this area over the past 100 years many experiments have been poorly designed because they have been developed on the premise that patients with AIS all have the same, single underlying cause despite much evidence to the contrary. Consequently, much of the data in the literature can be challenged and perhaps explains the lack of significant progress. Certainly, the results from this previous research suggest strongly that a new approach needs to be adopted or the same confusing results will continue to be collected and little progress will be made. There are certain areas of research that hold the greatest potential for success in finding a cure. These are identified in this paper and included in a theoretical research laboratory. It is suggested that this laboratory need not be theoretical if modern, cheap communication systems were readily adopted throughout the world and if people were willing to share ideas readily and contact each other regularly. In perhaps an unconventional way, the emphasis of this paper is on finding a cure to prevent scoliosis from developing and uses the area of research into the aetiology of scoliosis as the platform for discussion.

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Year:  2008        PMID: 18401081

Source DB:  PubMed          Journal:  Stud Health Technol Inform        ISSN: 0926-9630


  4 in total

1.  Pathogenesis of adolescent idiopathic scoliosis in girls - a double neuro-osseous theory involving disharmony between two nervous systems, somatic and autonomic expressed in the spine and trunk: possible dependency on sympathetic nervous system and hormones with implications for medical therapy.

Authors:  R Geoffrey Burwell; Ranjit K Aujla; Michael P Grevitt; Peter H Dangerfield; Alan Moulton; Tabitha L Randell; Susan I Anderson
Journal:  Scoliosis       Date:  2009-10-31

Review 2.  2016 SOSORT guidelines: orthopaedic and rehabilitation treatment of idiopathic scoliosis during growth.

Authors:  Stefano Negrini; Sabrina Donzelli; Angelo Gabriele Aulisa; Dariusz Czaprowski; Sanja Schreiber; Jean Claude de Mauroy; Helmut Diers; Theodoros B Grivas; Patrick Knott; Tomasz Kotwicki; Andrea Lebel; Cindy Marti; Toru Maruyama; Joe O'Brien; Nigel Price; Eric Parent; Manuel Rigo; Michele Romano; Luke Stikeleather; James Wynne; Fabio Zaina
Journal:  Scoliosis Spinal Disord       Date:  2018-01-10

3.  2011 SOSORT guidelines: Orthopaedic and Rehabilitation treatment of idiopathic scoliosis during growth.

Authors:  Stefano Negrini; Angelo G Aulisa; Lorenzo Aulisa; Alin B Circo; Jean Claude de Mauroy; Jacek Durmala; Theodoros B Grivas; Patrick Knott; Tomasz Kotwicki; Toru Maruyama; Silvia Minozzi; Joseph P O'Brien; Dimitris Papadopoulos; Manuel Rigo; Charles H Rivard; Michele Romano; James H Wynne; Monica Villagrasa; Hans-Rudolf Weiss; Fabio Zaina
Journal:  Scoliosis       Date:  2012-01-20

4.  On the linear sizes of vertebrae and intervertebral discs of children in the beginning of puberty.

Authors:  Mikhail Dudin; Yuri Baloshin; Igor Popov; Nikita Lisitsa; Stepan Bober
Journal:  J Craniovertebr Junction Spine       Date:  2018 Oct-Dec
  4 in total

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