BACKGROUND/ PURPOSE: Studies of the safety and efficacy of drug-eluting stent (DES) implantation to treat vertebral artery (VA) ostial stenosis are lacking in the Asian population. The aim of this study was to evaluate the feasibility and safety of DES implantation to treat VA ostial stenosis in Asians. METHODS: We retrospectively analyzed the medical and radiologic records of patients receiving VA origin stenting with DES from October 2004 to September 2006 in the National Taiwan University Hospital. RESULTS: Eleven symptomatic patients (9 male; mean age, 72 years) with 11 lesions treated with DES were included. There were eight lesions treated with paclitaxel-eluting stents and three lesions treated with sirolimus-eluting stents. The success rate for implantation of a DES was 100%. The percentage of stenosis was significantly reduced after stenting (86+/-5 to 2+/-4%; p<0.001). No peri-interventional neurologic, vascular, or other medical complications were noted. All patients were asymptomatic at the mean follow-up time of 18.7+/-8.6 months (range, 6-30 months). Two patients received repeat angiography at 4 or 8 months after stenting. No significant in-stent restenosis was found. CONCLUSION: Symptomatic VA origin stenosis can be treated safely and effectively with DES in Asians.
BACKGROUND/ PURPOSE: Studies of the safety and efficacy of drug-eluting stent (DES) implantation to treat vertebral artery (VA) ostial stenosis are lacking in the Asian population. The aim of this study was to evaluate the feasibility and safety of DES implantation to treat VA ostial stenosis in Asians. METHODS: We retrospectively analyzed the medical and radiologic records of patients receiving VA origin stenting with DES from October 2004 to September 2006 in the National Taiwan University Hospital. RESULTS: Eleven symptomatic patients (9 male; mean age, 72 years) with 11 lesions treated with DES were included. There were eight lesions treated with paclitaxel-eluting stents and three lesions treated with sirolimus-eluting stents. The success rate for implantation of a DES was 100%. The percentage of stenosis was significantly reduced after stenting (86+/-5 to 2+/-4%; p<0.001). No peri-interventional neurologic, vascular, or other medical complications were noted. All patients were asymptomatic at the mean follow-up time of 18.7+/-8.6 months (range, 6-30 months). Two patients received repeat angiography at 4 or 8 months after stenting. No significant in-stent restenosis was found. CONCLUSION: Symptomatic VA origin stenosis can be treated safely and effectively with DES in Asians.
Authors: Sun Young Chung; Deok Hee Lee; Jin Woo Choi; Byung Se Choi; Hyun Sin In; Sun Mi Kim; Choong Gon Choi; Sang Joon Kim; Dae Chul Suh Journal: Korean J Radiol Date: 2010-02-22 Impact factor: 3.500
Authors: Man Kwun Andrew Li; Anderson Chun On Tsang; Frederick Chun Pong Tsang; Wai Shing Ho; Raymand Lee; Gilberto Ka Kit Leung; Wai Man Lui Journal: Clin Neuroradiol Date: 2018-07-23 Impact factor: 3.649
Authors: Z Vajda; E Miloslavski; T Güthe; S Fischer; G Albes; A Heuschmid; H Henkes Journal: AJNR Am J Neuroradiol Date: 2009-09-03 Impact factor: 3.825