BACKGROUND: This study aimed to investigate temperament and character correlates of panic disorder (PD) comorbidity in euthymic patients with bipolar disorder (BD) or unipolar depression (UD). METHODS: Temperament and character were assessed using the Temperament and Character Inventory Revised (TCI-R) in 181 patients (70 patients with BD-I, 51 patients with BD-II and 60 with UD) in a euthymic state for at least 2 months. RESULTS: PD was diagnosed in 14.3% of BD-I patients, 31.4% of BD-II and 40% of UD. BD patients with PD, when compared with BD patients without PD, had higher scores on harm avoidance (OR=1.04; 95% CI=1.02-1.07; p=0.002). Patients with UD and PD, when compared to patients with UD without PD, had higher scores on social acceptance (OR=1.27; 95% CI=1.08-1.49; p=0.004). CONCLUSION: Different temperament and character dimensions correlated with PD comorbidity in BD and UD patients, suggesting different underlying pathophysiological mechanisms.
BACKGROUND: This study aimed to investigate temperament and character correlates of panic disorder (PD) comorbidity in euthymic patients with bipolar disorder (BD) or unipolar depression (UD). METHODS: Temperament and character were assessed using the Temperament and Character Inventory Revised (TCI-R) in 181 patients (70 patients with BD-I, 51 patients with BD-II and 60 with UD) in a euthymic state for at least 2 months. RESULTS:PD was diagnosed in 14.3% of BD-I patients, 31.4% of BD-II and 40% of UD. BD patients with PD, when compared with BD patients without PD, had higher scores on harm avoidance (OR=1.04; 95% CI=1.02-1.07; p=0.002). Patients with UD and PD, when compared to patients with UD without PD, had higher scores on social acceptance (OR=1.27; 95% CI=1.08-1.49; p=0.004). CONCLUSION: Different temperament and character dimensions correlated with PD comorbidity in BD and UD patients, suggesting different underlying pathophysiological mechanisms.
Authors: G B Cassano; A Benvenuti; M Miniati; S Calugi; M Mula; L Maggi; P Rucci; A Fagiolini; F Perris; E Frank Journal: J Affect Disord Date: 2008-10-22 Impact factor: 4.839
Authors: Antonio Bruno; Maria Rosaria Anna Muscatello; Gianluca Pandolfo; Giulia La Ciura; Diego Quattrone; Giuseppe Scimeca; Carmela Mento; Rocco A Zoccali Journal: Noro Psikiyatr Ars Date: 2018-07-06 Impact factor: 1.339
Authors: Hale Yapici Eser; Anil S Kacar; Can M Kilciksiz; Merve Yalçinay-Inan; Dost Ongur Journal: Front Psychiatry Date: 2018-06-27 Impact factor: 4.157