| Literature DB >> 18400251 |
Nischalan Pillay1, Pratistadevi K Ramdial, Kumarasen Cooper, David Batuule.
Abstract
Mucinous tubular and spindle cell carcinoma (MTSCC) is a recently described renal epithelial tumor. The bland cytomorphology of the spindled component and low-grade behavior help in its differentiation from sarcomatoid renal carcinoma. Sarcomatoid change has been reported in most histologic variants of renal cell carcinoma apart from MTSCC. Herein we report a case of an MTSCC in a 72-year-old female patient with high-grade spindled areas resembling fibrosarcomatous and undifferentiated pleomorphic sarcoma patterns with metaplastic bone. This index case also demonstrates a high proliferation index and extensive necrosis representing the first documented case of sarcomatoid change in MTSCC.Entities:
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Year: 2008 PMID: 18400251 DOI: 10.1016/j.humpath.2007.10.006
Source DB: PubMed Journal: Hum Pathol ISSN: 0046-8177 Impact factor: 3.466