Literature DB >> 18400188

The biological functions of T helper 17 cell effector cytokines in inflammation.

Wenjun Ouyang1, Jay K Kolls, Yan Zheng.   

Abstract

T helper 17 (Th17) cells belong to a recently identified T helper subset, in addition to the traditional Th1 and Th2 subsets. These cells are characterized as preferential producers of interleukin-17A (IL-17A), IL-17F, IL-21, and IL-22. Th17 cells and their effector cytokines mediate host defensive mechanisms to various infections, especially extracellular bacteria infections, and are involved in the pathogenesis of many autoimmune diseases. The receptors for IL-17 and IL-22 are broadly expressed on various epithelial tissues. The effector cytokines of Th17 cells, therefore, mediate the crucial crosstalk between immune system and tissues, and play indispensable roles in tissue immunity.

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Year:  2008        PMID： 18400188      PMCID： PMC3424508          DOI： 10.1016/j.immuni.2008.03.004

Source DB:  PubMed          Journal:  Immunity        ISSN： 1074-7613            Impact factor:   31.745


  164 in total

1.  Identification of the IL-17 receptor related molecule IL-17RC as the receptor for IL-17F.

Authors:  Rolf E Kuestner; David W Taft; Aaron Haran; Cameron S Brandt; Ty Brender; Karen Lum; Brandon Harder; Shannon Okada; Craig D Ostrander; James L Kreindler; Shean J Aujla; Brian Reardon; Margaret Moore; Pamela Shea; Randall Schreckhise; Thomas R Bukowski; Scott Presnell; Patricia Guerra-Lewis; Julia Parrish-Novak; Jeff L Ellsworth; Stephen Jaspers; Katherine E Lewis; Mark Appleby; Jay K Kolls; Mark Rixon; James W West; Zeren Gao; Steven D Levin
Journal:  J Immunol       Date:  2007-10-15       Impact factor: 5.422

2.  IL-17 enhances chemokine gene expression through mRNA stabilization.

Authors:  Justin Hartupee; Caini Liu; Michael Novotny; Xiaoxia Li; Thomas Hamilton
Journal:  J Immunol       Date:  2007-09-15       Impact factor: 5.422

3.  Requirement for both JAK-mediated PI3K signaling and ACT1/TRAF6/TAK1-dependent NF-kappaB activation by IL-17A in enhancing cytokine expression in human airway epithelial cells.

Authors:  Fei Huang; Cheng-Yuan Kao; Shinichiro Wachi; Philip Thai; Jisu Ryu; Reen Wu
Journal:  J Immunol       Date:  2007-11-15       Impact factor: 5.422

4.  Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation.

Authors:  Hania Kebir; Katharina Kreymborg; Igal Ifergan; Aurore Dodelet-Devillers; Romain Cayrol; Monique Bernard; Fabrizio Giuliani; Nathalie Arbour; Burkhard Becher; Alexandre Prat
Journal:  Nat Med       Date:  2007-09-09       Impact factor: 53.440

5.  IL-23 and the Th17 pathway promote inflammation and impair antifungal immune resistance.

Authors:  Teresa Zelante; Antonella De Luca; Pierluigi Bonifazi; Claudia Montagnoli; Silvia Bozza; Silvia Moretti; Maria L Belladonna; Carmine Vacca; Carmela Conte; Paolo Mosci; Francesco Bistoni; Paolo Puccetti; Robert A Kastelein; Manfred Kopf; Luigina Romani
Journal:  Eur J Immunol       Date:  2007-10       Impact factor: 5.532

6.  An IL-17F/A heterodimer protein is produced by mouse Th17 cells and induces airway neutrophil recruitment.

Authors:  Spencer C Liang; Andrew J Long; Frann Bennett; Matthew J Whitters; Riyez Karim; Mary Collins; Samuel J Goldman; Kyriaki Dunussi-Joannopoulos; Cara M M Williams; Jill F Wright; Lynette A Fouser
Journal:  J Immunol       Date:  2007-12-01       Impact factor: 5.422

Review 7.  Protective immune mechanisms in helminth infection.

Authors:  Robert M Anthony; Laura I Rutitzky; Joseph F Urban; Miguel J Stadecker; William C Gause
Journal:  Nat Rev Immunol       Date:  2007-12       Impact factor: 53.106

8.  IL-22 is expressed by Th17 cells in an IL-23-dependent fashion, but not required for the development of autoimmune encephalomyelitis.

Authors:  Katharina Kreymborg; Ruth Etzensperger; Laure Dumoutier; Stefan Haak; Angelita Rebollo; Thorsten Buch; Frank L Heppner; Jean-Christophe Renauld; Burkhard Becher
Journal:  J Immunol       Date:  2007-12-15       Impact factor: 5.422

9.  Cytokine-mediated regulation of human B cell differentiation into Ig-secreting cells: predominant role of IL-21 produced by CXCR5+ T follicular helper cells.

Authors:  Vanessa L Bryant; Cindy S Ma; Danielle T Avery; Ying Li; Kim L Good; Lynn M Corcoran; Rene de Waal Malefyt; Stuart G Tangye
Journal:  J Immunol       Date:  2007-12-15       Impact factor: 5.422

10.  Interleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammation.

Authors:  Lauren A Zenewicz; George D Yancopoulos; David M Valenzuela; Andrew J Murphy; Margaret Karow; Richard A Flavell
Journal:  Immunity       Date:  2007-10-04       Impact factor: 31.745
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  665 in total

1.  IL-17-producing innate lymphoid cells are restricted to mucosal tissues and are depleted in SIV-infected macaques.

Authors:  H Xu; X Wang; D X Liu; T Moroney-Rasmussen; A A Lackner; R S Veazey
Journal:  Mucosal Immunol       Date:  2012-06-06       Impact factor: 7.313

Review 2.  Tumor-infiltrating lymphocytes and hepatocellular carcinoma: molecular biology.

Authors:  Nobuyoshi Hiraoka
Journal:  Int J Clin Oncol       Date:  2010-10-06       Impact factor: 3.402

Review 3.  Interleukin-23 and T helper 17-type responses in intestinal inflammation: from cytokines to T-cell plasticity.

Authors:  Peter J Morrison; Sarah J Ballantyne; Marika C Kullberg
Journal:  Immunology       Date:  2011-06-02       Impact factor: 7.397

4.  Macrophages participate in IL-17-mediated inflammation.

Authors:  Jobert G Barin; G Christian Baldeviano; Monica V Talor; Lei Wu; Sufey Ong; Farhan Quader; Ping Chen; Dongfeng Zheng; Patrizio Caturegli; Noel R Rose; Daniela Ciháková
Journal:  Eur J Immunol       Date:  2012-01-23       Impact factor: 5.532

5.  Role of antibodies in Sm-p80-mediated protection against Schistosoma mansoni challenge infection in murine and nonhuman primate models.

Authors:  Workineh Torben; Gul Ahmad; Weidong Zhang; Afzal A Siddiqui
Journal:  Vaccine       Date:  2011-01-28       Impact factor: 3.641

6.  Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammation.

Authors:  Ashutosh Chaudhry; Robert M Samstein; Piper Treuting; Yuqiong Liang; Marina C Pils; Jan-Michael Heinrich; Robert S Jack; F Thomas Wunderlich; Jens C Brüning; Werner Müller; Alexander Y Rudensky
Journal:  Immunity       Date:  2011-04-22       Impact factor: 31.745

7.  Mouse CD11b+Gr-1+ myeloid cells can promote Th17 cell differentiation and experimental autoimmune encephalomyelitis.

Authors:  Huanfa Yi; Chunqing Guo; Xiaofei Yu; Daming Zuo; Xiang-Yang Wang
Journal:  J Immunol       Date:  2012-10-03       Impact factor: 5.422

8.  Phenotype and Antimicrobial Activity of Th17 Cells Induced by Propionibacterium acnes Strains Associated with Healthy and Acne Skin.

Authors:  George W Agak; Stephanie Kao; Kelsey Ouyang; Min Qin; David Moon; Ahsan Butt; Jenny Kim
Journal:  J Invest Dermatol       Date:  2017-08-31       Impact factor: 8.551

Review 9.  IL-17F: regulation, signaling and function in inflammation.

Authors:  Seon Hee Chang; Chen Dong
Journal:  Cytokine       Date:  2009-02-23       Impact factor: 3.861

10.  IL-25 dampens the growth of human germinal center-derived B-cell non Hodgkin Lymphoma by curtailing neoangiogenesis.

Authors:  Elisa Ferretti; Emma Di Carlo; Emanuela Ognio; Giulio Fraternali-Orcioni; Anna Corcione; Beatrice Belmonte; Jean Louis Ravetti; Claudio Tripodo; Domenico Ribatti; Vito Pistoia
Journal:  Oncoimmunology       Date:  2017-11-27       Impact factor: 8.110
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