Literature DB >> 18400186

Cytokines as therapeutic targets: advances and limitations.

Clemens Scheinecker1, Kurt Redlich, Josef S Smolen.   

Abstract

Biological therapies targeting cytokines, T cells, or B cells have improved outcomes of inflammatory diseases. However, many issues remain open: What is the best target? How well can response be predicted? How can cure be achieved?

Mesh：

Substances：

Year:  2008        PMID： 18400186     DOI： 10.1016/j.immuni.2008.03.005

Source DB:  PubMed          Journal:  Immunity        ISSN： 1074-7613            Impact factor:   31.745


  19 in total

Review 1.  Rheumatoid arthritis therapy reappraisal: strategies, opportunities and challenges.

Authors:  Josef S Smolen; Daniel Aletaha
Journal:  Nat Rev Rheumatol       Date:  2015-02-17       Impact factor: 20.543

Review 2.  New insights into T cell biology and T cell-directed therapy for autoimmunity, inflammation, and immunosuppression.

Authors:  Scott M Steward-Tharp; Yun-jeong Song; Richard M Siegel; John J O'Shea
Journal:  Ann N Y Acad Sci       Date:  2010-01       Impact factor: 5.691

3.  Inhibitor of apoptosis proteins (IAPs) and their antagonists regulate spontaneous and tumor necrosis factor (TNF)-induced proinflammatory cytokine and chemokine production.

Authors:  Conor J Kearney; Clare Sheridan; Sean P Cullen; Graham A Tynan; Susan E Logue; Inna S Afonina; Domagoj Vucic; Ed C Lavelle; Seamus J Martin
Journal:  J Biol Chem       Date:  2012-12-28       Impact factor: 5.157

4.  Advanced glycation end products induce the expression of interleukin-6 and interleukin-8 by receptor for advanced glycation end product-mediated activation of mitogen-activated protein kinases and nuclear factor-κB in human osteoarthritis chondrocytes.

Authors:  Zafar Rasheed; Nahid Akhtar; Tariq M Haqqi
Journal:  Rheumatology (Oxford)       Date:  2010-12-20       Impact factor: 7.580

Review 5.  Monitoring of inflammation in patients on dialysis: forewarned is forearmed.

Authors:  Christiaan L Meuwese; Peter Stenvinkel; Friedo W Dekker; Juan J Carrero
Journal:  Nat Rev Nephrol       Date:  2011-03       Impact factor: 28.314

6.  Tolerance induction using lentiviral gene delivery delays onset and severity of collagen II arthritis.

Authors:  Inger Gjertsson; Karen L Laurie; James Devitt; Steven J Howe; Adrian J Thrasher; Rikard Holmdahl; Kenth Gustafsson
Journal:  Mol Ther       Date:  2009-01-27       Impact factor: 11.454

Review 7.  Cytokines and cytokine profiles in human autoimmune diseases and animal models of autoimmunity.

Authors:  Manfred Kunz; Saleh M Ibrahim
Journal:  Mediators Inflamm       Date:  2009-10-26       Impact factor: 4.711

8.  Induction of macrophage migration inhibitory factor in ConA-stimulated rheumatoid arthritis synovial fibroblasts through the P38 map kinase-dependent signaling pathway.

Authors:  Hae-Rim Kim; Mi-Kyung Park; Mi-La Cho; Kyoung-Woon Kim; Hye-Joa Oh; Jin-Sil Park; Yang-Mi Heo; Sang-Heon Lee; Ho-Youn Kim; Sung-Hwan Park
Journal:  Korean J Intern Med       Date:  2010-08-31       Impact factor: 3.165

9.  An overview of cytokines and cytokine antagonists as therapeutic agents.

Authors:  Raymond P Donnelly; Howard A Young; Amy S Rosenberg
Journal:  Ann N Y Acad Sci       Date:  2009-12       Impact factor: 5.691

10.  Macrophage migration inhibitory factor stimulates interleukin-17 expression and production in lymph node cells.

Authors:  Ivana Stojanović; Tamara Cvjetićanin; Sandra Lazaroski; Stanislava Stosić-Grujicić; Djordje Miljković
Journal:  Immunology       Date:  2008-06-20       Impact factor: 7.397
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