Literature DB >> 18400059

Heterogeneity in antisocial behaviours and comorbidity with depressed mood: a behavioural genetic approach.

Richard Rowe1, Fruhling V Rijsdijk, Barbara Maughan, Thalia C Eley, Georgina M Hosang, Thalia C Eley.   

Abstract

BACKGROUND: Antisocial behaviour is often comorbid with depressed mood but is itself a collection of heterogeneous behaviours. Using a genetically informative design, we examine heterogeneity in antisocial behaviour and overlaps between different forms of antisocial behaviour with depressed mood.
METHODS: Data were drawn from the G1219 large-scale community sample containing self-report questionnaire data from 941 twin pairs and 328 sibling-pairs aged 12-21 years.
RESULTS: Inter-correlations among oppositionality, physical aggression and delinquency, and between the antisocial subscales and depressed mood, were mediated by genetic and non-shared environmental influences. Genetic factors generally contributed more to the correlations than the non-shared environment.
CONCLUSIONS: These results indicate that many genetic and non-shared environmental influences were common to all the traits studied, but there was also evidence for trait-specific effects.

Entities:  

Mesh:

Year:  2008        PMID: 18400059     DOI: 10.1111/j.1469-7610.2008.01834.x

Source DB:  PubMed          Journal:  J Child Psychol Psychiatry        ISSN: 0021-9630            Impact factor:   8.982


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