Literature DB >> 18399328

An integrative approach for biological data mining and visualisation.

Peddinti V Gopalacharyulu1, Erno Lindfors, Jarkko Miettinen, Catherine K Bounsaythip, Matej Oresic.   

Abstract

The emergence of systems biology necessitates development of platforms to organise and interpret plentitude of biological data. We present a system to integrate data across multiple bioinformatics databases and enable mining across various conceptual levels of biological information. The results are represented as complex networks. Context dependent mining of these networks is achieved by use of distances. Our approach is demonstrated with three applications: full metabolic network retrieval with network topology study, exploration of properties and relationships of a set of selected proteins, and combined visualisation and exploration of gene expression data with related pathways and ontologies.

Mesh:

Year:  2008        PMID: 18399328     DOI: 10.1504/ijdmb.2008.016756

Source DB:  PubMed          Journal:  Int J Data Min Bioinform        ISSN: 1748-5673            Impact factor:   0.667


  6 in total

1.  Biomedical ontologies in action: role in knowledge management, data integration and decision support.

Authors:  O Bodenreider
Journal:  Yearb Med Inform       Date:  2008

2.  An attempt to construct a (general) mathematical framework to model biological "context-dependence".

Authors:  Anirban Banerji
Journal:  Syst Synth Biol       Date:  2013-08-28

3.  Determining and interpreting correlations in lipidomic networks found in glioblastoma cells.

Authors:  Robert Görke; Anke Meyer-Bäse; Dorothea Wagner; Huan He; Mark R Emmett; Charles A Conrad
Journal:  BMC Syst Biol       Date:  2010-09-07

4.  Differential network analysis with multiply imputed lipidomic data.

Authors:  Maiju Kujala; Jaakko Nevalainen; Winfried März; Reijo Laaksonen; Susmita Datta
Journal:  PLoS One       Date:  2015-03-30       Impact factor: 3.240

Review 5.  "Gestaltomics": Systems Biology Schemes for the Study of Neuropsychiatric Diseases.

Authors:  Nora A Gutierrez Najera; Osbaldo Resendis-Antonio; Humberto Nicolini
Journal:  Front Physiol       Date:  2017-05-09       Impact factor: 4.566

6.  Detection of molecular paths associated with insulitis and type 1 diabetes in non-obese diabetic mouse.

Authors:  Erno Lindfors; Peddinti V Gopalacharyulu; Eran Halperin; Matej Oresic
Journal:  PLoS One       Date:  2009-10-02       Impact factor: 3.240

  6 in total

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