Literature DB >> 18399155

[Study on the association of clinical characteristic, CD4+ and level of HIV viral load among 690 initial HIV-infection].

Yan-chun Liu1, Xing-hong Li, Xing-wang Li, Wen-hui Lun, Hui-wen Yan, Meng-liang Ge, Xue-jun Zhu.   

Abstract

OBJECTIVE: To understand the correlation between CD4+ cell count, HIV viral load (VL) and clinical characteristics among patients when HIV-1 was tested positive and initial AIDS diagnosis was made.
METHODS: 690 HIV-infected cases from Beijing Di-Tan Hospital were included and under a cross sectional study while SPSS statistical method was used.
RESULTS: The 690 HIV-infected cases would include 458 males and 232 females with age range from 2-72 years (mean age as 35.3). The modes of transmission showed that: homosexual contact taking up 17.5% while heterosexual was 16.7%. Most of the homosexual-infected ones lived in Beijing and most of them had bachelor or master's degrees. 19.4% of the transmission happened between heterosexual/bisexual couples, suggesting that HIV was transmitted through the "bridge population" while the rest were infected by contaminated blood/plasma. Many of the cases were identified when they lately visited the pre-operation surveillance point in the hospital. Serious immunodeficiency symptoms or signs were discovered as: CD4+ count < 50 cell/microl, serious opportunistic infections including pneumocystosis pulmonary, cerebral toxoplasmosis and cryptococcal meningitis. Higher frequencies of diseases seen were dermotosis, pneumonia, upper respiratory tract infection, hepatitis and digestive tract moniliasis.
CONCLUSION: Because of the late identification of the disease, serious immuo-suppression situation often appeared, suggesting that there was an urgent need to improve STD/AIDS knowledge on those HIV (+) people so they might have an early access to accept medical care.

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Year:  2007        PMID: 18399155

Source DB:  PubMed          Journal:  Zhonghua Liu Xing Bing Xue Za Zhi        ISSN: 0254-6450


  1 in total

1.  Toxoplasmosis with chorioretinitis in an HIV-infected child with no visual complaints-importance of fundus examination.

Authors:  Noella Maria Delia Pereira; Ira Shah; Mamatha Lala
Journal:  Oxf Med Case Reports       Date:  2017-01-03
  1 in total

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