| Literature DB >> 18398737 |
Je-Hwan Lee1, Yoo Hong Min, Chul Won Chung, Byoung Kook Kim, Hwi-Joong Yoon, Deog-Yeon Jo, Ho-Jin Shin, Soo-Mee Bang, Jong-Ho Won, Dae Young Zang, Hyeoung Joon Kim, Hyun-Sook Chi, Kyoo-Hyung Lee, June-Won Cheong, Jin Seok Kim, Sun Hee Kim, Seonyang Park, Su Yon Park, Joo Seop Chung, Jae Hoon Lee, Chan-Jeoung Park.
Abstract
The present study retrospectively analyzed clinicopathological and clinical data from 43 adult patients with biphenotypic acute leukemia (BAL) from 11 Korean institutes. The incidence of BAL was 2.1% among acute leukemias. In terms of immunophenotype, 31 patients had myeloid plus B-lymphoid (M + B), 10 had myeloid plus T-lymphoid (M + T), one had myeloid plus B-lymphoid plus T-lymphoid (M + B + T), and one had B-lymphoid plus T-lymphoid (B + T). Patients with M + T phenotype had significantly lower CR rate (55.6% vs. 88.0%, P = 0.039) and lower overall survival (0% vs. 33.9% at 5 years, P = 0.028) than those with M + B phenotype. Our results suggest that immunophenotype has prognostic implications in adult patients with BAL.Entities:
Mesh：
Substances：
Year: 2008 PMID： 18398737 DOI： 10.1080/10428190701843247
Source DB: PubMed Journal: Leuk Lymphoma ISSN： 1026-8022