| Literature DB >> 18397740 |
Abstract
Innate immunity to viruses involves receptors such as RIG-I, which senses viral RNA and triggers a signalling pathway involving the outer mitochondrial membrane protein MAVS. Recent work has identified that NLRX1, a member of another class of innate immune receptors, sequesters MAVS away from RIG-I and thereby prevents mitochondrial anti-viral immunity.Entities:
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Year: 2008 PMID： 18397740 DOI： 10.1016/j.cub.2008.02.021
Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834