Literature DB >> 18397628

[Somatostatin analogues in the treatment of bleeding GI-angiodysplasias].

Lene Boesby1, Niels Juel Christensen, Lars Ostergaard Kristensen.   

Abstract

Angiodysplasias account for 2-8% of GI-bleeding episodes. We describe a 75-year-old patient with a history of anaemia for 1 year before being diagnosed with multiple angiodysplasias in the GI-tract. The patient needed weekly blood transfusions until he started treatment with octreotide. After 4 months of treatment the need for transfusions had decreased dramatically and faeces was negative for blood. Treatment was switched to long-acting octreotide (Sandostatin Lar). The case illustrates the usefulness of somatostatin analogues in the treatment of bleeding GI-angiodysplasias.

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Year:  2008        PMID: 18397628

Source DB:  PubMed          Journal:  Ugeskr Laeger        ISSN: 0041-5782


  4 in total

1.  Long-time octreotide in an adolescent with severe haemorrhagic gastrointestinal vascular malformation.

Authors:  Carl Friedrich Classen; Dieter Haffner; Christina Hauenstein; Ricarda Wolf; Ulrike Kyank
Journal:  BMJ Case Rep       Date:  2011-08-17

2.  Characteristics of gastrointestinal bleeding after placement of continuous-flow left ventricular assist device: a case series.

Authors:  Joseph Marsano; Jay Desai; Shannon Chang; Michelle Chau; Mark Pochapin; Grigoriy E Gurvits
Journal:  Dig Dis Sci       Date:  2015-01-24       Impact factor: 3.199

3.  Severe Gastrointestinal Bleeding in a Patient With Subvalvular Aortic Stenosis Treated With Thalidomide and Octreotide: Bridging to Transcoronary Ablation of Septal Hypertrophy.

Authors:  Helene S Hvid-Jensen; Steen H Poulsen; Jorgen S Agnholt
Journal:  J Clin Med Res       Date:  2015-09-25

4.  Efficacy and safety of pasireotide-LAR for the treatment of refractory bleeding due to gastrointestinal angiodysplasias: results of the ANGIOPAS multicenter phase II noncomparative prospective double-blinded randomized study.

Authors:  Robert Benamouzig; Mourad Benallaoua; Jean-Christophe Saurin; Marouane Boubaya; Christophe Cellier; René Laugier; Magalie Vincent; Christian Boustière; Rodica Gincul; Elia Samaha; Philippe Grandval; Thomas Aparicio; Gheorghe Airinei; Bakhtiar Bejou; Cyriaque Bon; Jean-Jacques Raynaud; Vincent Levy; Denis Sautereau
Journal:  Therap Adv Gastroenterol       Date:  2018-02-16       Impact factor: 4.409

  4 in total

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