BACKGROUND: Determining the role of pre- and perinatal factors in the aetiology of childhood malignant central nervous (CNS) tumors, using data from the French national case-control study, ESCALE. METHODS: ESCALE included all children in France less than 15 years old with a diagnosis of acute leukaemia, lymphoma, malignant CNS tumor, or neuroblastoma (2003-2004). In all, 209 malignant CNS tumor cases (80% of the eligible cases) and 1681 population-based controls (71%) were included using quotas ensuring frequency matching with the cases by age and gender. Case and control mothers were interviewed using a standardised telephone interview, which elicited birth characteristics, congenital malformation, maternal reproductive history, and use of assisted reproductive technologies for the index child. RESULTS: The cases and controls did not differ in terms of gestational age at birth, birth weight, birth order, breastfeeding, or parental age at birth. There was no association between assisted reproduction for the index child and malignant CNS tumor (OR=1.1 [0.6-2.2]). A positive association between a maternal history of one miscarriage and malignant CNS tumor was observed (OR=1.4 [1.0-2.0], p<0.05), especially for glial cell tumors (other glioma: OR=2.0 [1.1-3.6]). CONCLUSION: The results suggest a possible association between a maternal history of one miscarriage and the risk of malignant CNS tumor.
BACKGROUND: Determining the role of pre- and perinatal factors in the aetiology of childhood malignant central nervous (CNS) tumors, using data from the French national case-control study, ESCALE. METHODS: ESCALE included all children in France less than 15 years old with a diagnosis of acute leukaemia, lymphoma, malignant CNS tumor, or neuroblastoma (2003-2004). In all, 209 malignant CNS tumor cases (80% of the eligible cases) and 1681 population-based controls (71%) were included using quotas ensuring frequency matching with the cases by age and gender. Case and control mothers were interviewed using a standardised telephone interview, which elicited birth characteristics, congenital malformation, maternal reproductive history, and use of assisted reproductive technologies for the index child. RESULTS: The cases and controls did not differ in terms of gestational age at birth, birth weight, birth order, breastfeeding, or parental age at birth. There was no association between assisted reproduction for the index child and malignant CNS tumor (OR=1.1 [0.6-2.2]). A positive association between a maternal history of one miscarriage and malignant CNS tumor was observed (OR=1.4 [1.0-2.0], p<0.05), especially for glial cell tumors (other glioma: OR=2.0 [1.1-3.6]). CONCLUSION: The results suggest a possible association between a maternal history of one miscarriage and the risk of malignant CNS tumor.
Authors: Kimberly J Johnson; Jong Min Lee; Kazi Ahsan; Hannah Padda; Qianxi Feng; Sonia Partap; Susan A Fowler; Todd E Druley Journal: PLoS One Date: 2017-07-27 Impact factor: 3.240
Authors: Julie Von Behren; Logan G Spector; Beth A Mueller; Susan E Carozza; Eric J Chow; Erin E Fox; Scott Horel; Kimberly J Johnson; Colleen McLaughlin; Susan E Puumala; Julie A Ross; Peggy Reynolds Journal: Int J Cancer Date: 2010-10-08 Impact factor: 7.396
Authors: L S Schmidt; M Kamper-Jørgensen; K Schmiegelow; C Johansen; P Lähteenmäki; C Träger; T Stokland; K Grell; G Gustafson; P Kogner; A Sehested; J Schüz Journal: Br J Cancer Date: 2010-05-11 Impact factor: 7.640
Authors: Rong Wang; Catherine Metayer; Libby Morimoto; Joseph L Wiemels; Juan Yang; Andrew T DeWan; Alice Kang; Xiaomei Ma Journal: Am J Epidemiol Date: 2017-10-01 Impact factor: 5.363
Authors: Åsa Magnusson; Hannele Laivuori; Anne Loft; Nan B Oldereid; Anja Pinborg; Max Petzold; Liv Bente Romundstad; Viveca Söderström-Anttila; Christina Bergh Journal: Front Pediatr Date: 2021-06-23 Impact factor: 3.418
Authors: Lorenzo D Botto; Timothy Flood; Julian Little; Mark N Fluchel; Sergey Krikov; Marcia L Feldkamp; Yuan Wu; Rhinda Goedken; Soman Puzhankara; Paul A Romitti Journal: PLoS One Date: 2013-07-17 Impact factor: 3.240