OBJECTIVE: To describe the resolution of anejaculation associated with PRL excess by dopamine agonist treatment. DESIGN: Case report. SETTING: Fertility clinic. PATIENT(S): Two men with anejaculation, in one case with associated infertility. INTERVENTION(S): Dopamine agonist treatment. MAIN OUTCOME MEASURE(S): Resolution of anejaculation and infertility. RESULT(S): Endocrine investigations in both men revealed low serum T, elevated PRL, and a pituitary microadenoma. Treatment with a dopamine agonist normalized serum hormone profiles and restored sexual function, with subsequent involution of the adenoma. CONCLUSION(S): Prolactinoma manifesting as anejaculation is rare but responds readily to treatment with a dopamine agonist. Serum PRL should be measured in any man presenting with anejaculation.
OBJECTIVE: To describe the resolution of anejaculation associated with PRL excess by dopamine agonist treatment. DESIGN: Case report. SETTING: Fertility clinic. PATIENT(S): Two men with anejaculation, in one case with associated infertility. INTERVENTION(S): Dopamine agonist treatment. MAIN OUTCOME MEASURE(S): Resolution of anejaculation and infertility. RESULT(S): Endocrine investigations in both men revealed low serum T, elevated PRL, and a pituitary microadenoma. Treatment with a dopamine agonist normalized serum hormone profiles and restored sexual function, with subsequent involution of the adenoma. CONCLUSION(S): Prolactinoma manifesting as anejaculation is rare but responds readily to treatment with a dopamine agonist. Serum PRL should be measured in any man presenting with anejaculation.