| Literature DB >> 18393764 |
N N Sidorova1, A O Fadeev, A N Kuimov.
Abstract
We have isolated and purified endogenous cytosolic tankyrase from human embryonic kidney cells of line 293. Our data confirm a model of De Rycker and Price who consider that tankyrase is a master scaffolding protein capable of regulating assembly of large protein complexes. We have also studied kinetic characteristics of tankyrase in the complex, pH dependence of the enzyme activity, and its physicochemical properties.Entities:
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Year: 2008 PMID: 18393764 DOI: 10.1134/s0006297908030085
Source DB: PubMed Journal: Biochemistry (Mosc) ISSN: 0006-2979 Impact factor: 2.487