| Literature DB >> 18393518 |
Haibing Deng1, Xiaobao Yang, Zhaolong Tong, Zhong Li, Hongbin Zhai.
Abstract
An efficient eight-step assembly of the tetracyclic core (ABCD rings) of ent-(+)-nakadomarin A, a bioactive hexacyclic marine alkaloid, has been realized with Sonogashira coupling, platinum(II)-promoted cascade cyclizations, and saturation of a challenging carbon-carbon double bond through a hydroboration/oxidation/xanthate formation/Barton-McCombie deoxygenation sequence as key transformations.Entities:
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Year: 2008 PMID： 18393518 DOI： 10.1021/ol800579j
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005