Literature DB >> 18393402

Natural products as leads to potential drugs: an old process or the new hope for drug discovery?

David J Newman1.   

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Year:  2008        PMID: 18393402     DOI: 10.1021/jm0704090

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


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  157 in total

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Authors:  Fazlul H Sarkar
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Journal:  J Nat Prod       Date:  2010-04-23       Impact factor: 4.050

Review 3.  Strategies for the Optimization of Natural Leads to Anticancer Drugs or Drug Candidates.

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Review 4.  Natural products as sources of new drugs over the 30 years from 1981 to 2010.

Authors:  David J Newman; Gordon M Cragg
Journal:  J Nat Prod       Date:  2012-02-08       Impact factor: 4.050

5.  Gambogic acid inhibits STAT3 phosphorylation through activation of protein tyrosine phosphatase SHP-1: potential role in proliferation and apoptosis.

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6.  Natural products and drug discovery. Can thousands of years of ancient medical knowledge lead us to new and powerful drug combinations in the fight against cancer and dementia?

Authors:  Hong-Fang Ji; Xue-Juan Li; Hong-Yu Zhang
Journal:  EMBO Rep       Date:  2009-02-20       Impact factor: 8.807

Review 7.  Selective MAO-B inhibitors: a lesson from natural products.

Authors:  Simone Carradori; Melissa D'Ascenzio; Paola Chimenti; Daniela Secci; Adriana Bolasco
Journal:  Mol Divers       Date:  2013-11-12       Impact factor: 2.943

8.  Synthesis of skeletally diverse and stereochemically complex library templates derived from isosteviol and steviol.

Authors:  Oliver E Hutt; Trinh L Doan; Gunda I Georg
Journal:  Org Lett       Date:  2013-03-26       Impact factor: 6.005

9.  Molecular library synthesis using complex substrates: expanding the framework of triterpenoids.

Authors:  Vasily A Ignatenko; Yong Han; Gregory P Tochtrop
Journal:  J Org Chem       Date:  2013-01-10       Impact factor: 4.354

10.  SB365 inhibits angiogenesis and induces apoptosis of hepatocellular carcinoma through modulation of PI3K/Akt/mTOR signaling pathway.

Authors:  Sang-Won Hong; Kyung Hee Jung; Hee-Seung Lee; Myung-Joo Choi; Mi Kwon Son; Hong-Mei Zheng; Soon-Sun Hong
Journal:  Cancer Sci       Date:  2012-09-25       Impact factor: 6.716

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