Literature DB >> 18392684

Current therapeutic options for breast cancer central nervous system metastases.

M Brian Hemphill1, Julia A Lawrence.   

Abstract

OPINION STATEMENT: Breast cancer metastases to the central nervous system (CNS) has devastating consequences for the individual. As treatment options for metastatic breast cancer expand and as quality of life and overall survival improve, researchers are targeting potential treatments for this sanctuary site. Attention is now being focused on defining the phenotype of breast cancer that has a propensity to metastasize to the CNS. Specific therapies that penetrate the blood brain barrier as well as adjuvant therapies that decrease recurrence in the CNS are currently being investigated. We will review current approaches to the diagnosis, evaluation, and treatment of CNS metastases in breast cancer patients.

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Year:  2008        PMID： 18392684     DOI： 10.1007/s11864-008-0056-2

Source DB:  PubMed          Journal:  Curr Treat Options Oncol        ISSN： 1534-6277


  50 in total

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Journal:  Eur J Cancer       Date:  2004-12       Impact factor: 9.162

2.  Primary breast cancer phenotypes associated with propensity for central nervous system metastases.

Authors:  Yee-Lu Tham; Krystal Sexton; Rita Kramer; Susan Hilsenbeck; Richard Elledge
Journal:  Cancer       Date:  2006-08-15       Impact factor: 6.860

3.  Identifying breast cancer patients at risk for Central Nervous System (CNS) metastases in trials of the International Breast Cancer Study Group (IBCSG).

Authors:  B C Pestalozzi; D Zahrieh; K N Price; S B Holmberg; J Lindtner; J Collins; D Crivellari; M F Fey; E Murray; O Pagani; E Simoncini; M Castiglione-Gertsch; R D Gelber; A S Coates; A Goldhirsch
Journal:  Ann Oncol       Date:  2006-04-07       Impact factor: 32.976

4.  Risk factors for brain relapse in patients with metastatic breast cancer.

Authors:  K Slimane; F Andre; S Delaloge; A Dunant; A Perez; J Grenier; C Massard; M Spielmann
Journal:  Ann Oncol       Date:  2004-11       Impact factor: 32.976

5.  Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer.

Authors:  Martine J Piccart-Gebhart; Marion Procter; Brian Leyland-Jones; Aron Goldhirsch; Michael Untch; Ian Smith; Luca Gianni; Jose Baselga; Richard Bell; Christian Jackisch; David Cameron; Mitch Dowsett; Carlos H Barrios; Günther Steger; Chiun-Shen Huang; Michael Andersson; Moshe Inbar; Mikhail Lichinitser; István Láng; Ulrike Nitz; Hiroji Iwata; Christoph Thomssen; Caroline Lohrisch; Thomas M Suter; Josef Rüschoff; Tamás Suto; Victoria Greatorex; Carol Ward; Carolyn Straehle; Eleanor McFadden; M Stella Dolci; Richard D Gelber
Journal:  N Engl J Med       Date:  2005-10-20       Impact factor: 91.245

6.  Meningeal carcinomatosis in patients with breast carcinoma. Clinical features, prognostic factors, and results of a high-dose intrathecal methotrexate regimen.

Authors:  K Fizazi; B Asselain; A Vincent-Salomon; M Jouve; V Dieras; T Palangie; P Beuzeboc; T Dorval; P Pouillart
Journal:  Cancer       Date:  1996-04-01       Impact factor: 6.860

7.  Multiple brain metastases are associated with poor survival in patients treated with surgery and radiotherapy.

Authors:  M B Hazuka; W D Burleson; D N Stroud; C E Leonard; K O Lillehei; J J Kinzie
Journal:  J Clin Oncol       Date:  1993-02       Impact factor: 44.544

Review 8.  Diagnosis and management of central nervous system metastases from breast cancer.

Authors:  Eric L Chang; Simon Lo
Journal:  Oncologist       Date:  2003

9.  Neurocognitive and functional assessment of patients with brain metastases: a pilot study.

Authors:  Mary A Herman; Ivo Tremont-Lukats; Christina A Meyers; Dianna D Trask; Carrie Froseth; Markus F Renschler; Minesh P Mehta
Journal:  Am J Clin Oncol       Date:  2003-06       Impact factor: 2.339

Review 10.  Current therapeutic approaches in patients with brain metastases.

Authors:  Kevin H Peacock; Glenn J Lesser
Journal:  Curr Treat Options Oncol       Date:  2006-11
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  1 in total

1.  Combined alloreactive CTL cellular therapy with prodrug activator gene therapy in a model of breast cancer metastatic to the brain.

Authors:  Michelle J Hickey; Colin C Malone; Kate L Erickson; Amy Lin; Horacio Soto; Edward T Ha; Shuichi Kamijima; Akihito Inagaki; Masamichi Takahashi; Yuki Kato; Noriyuki Kasahara; Barbara M Mueller; Carol A Kruse
Journal:  Clin Cancer Res       Date:  2013-06-18       Impact factor: 12.531
  1 in total

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