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Literature DB >> 18392608

Profiling genes in the ICU: are we there yet?

Jérôme Pugin.

Abstract

Mesh：

Year: 2008 PMID： 18392608 DOI： 10.1007/s00134-008-1049-0

Source DB: PubMed Journal: Intensive Care Med ISSN： 0342-4642 Impact factor: 17.440

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15 in total

Review 1. Challenges of implementing pharmacogenetics in the critical care environment.

Authors: Bradley D Freeman; Howard L McLeod
Journal: Nat Rev Drug Discov Date: 2004-01 Impact factor: 84.694

2. A multiplex real-time PCR assay for rapid detection and differentiation of 25 bacterial and fungal pathogens from whole blood samples.

Authors: Lutz Eric Lehmann; Klaus-Peter Hunfeld; Thomas Emrich; Gerd Haberhausen; Heimo Wissing; Andreas Hoeft; Frank Stüber
Journal: Med Microbiol Immunol Date: 2007-11-16 Impact factor: 3.402

3. Genomics and critical care: do the right thing!

Authors: Frank Stuber
Journal: Crit Care Med Date: 2003-06 Impact factor: 7.598

4. Association of TNF2, a TNF-alpha promoter polymorphism, with septic shock susceptibility and mortality: a multicenter study.

Authors: J P Mira; A Cariou; F Grall; C Delclaux; M R Losser; F Heshmati; C Cheval; M Monchi; J L Teboul; F Riché; G Leleu; L Arbibe; A Mignon; M Delpech; J F Dhainaut
Journal: JAMA Date: 1999-08-11 Impact factor: 56.272

Profiling genes in the ICU: are we there yet?

Review 1. Challenges of implementing pharmacogenetics in the critical care environment.

2. A multiplex real-time PCR assay for rapid detection and differentiation of 25 bacterial and fungal pathogens from whole blood samples.

3. Genomics and critical care: do the right thing!

4. Association of TNF2, a TNF-alpha promoter polymorphism, with septic shock susceptibility and mortality: a multicenter study.

Review 5. The era of genomics: impact on sepsis clinical trial design.

6. Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock.

7. The use of gene-expression profiling to identify candidate genes in human sepsis.

8. Differential gene expression in gram-negative and gram-positive sepsis.

9. Gene expression profiles differentiate between sterile SIRS and early sepsis.

Review 10. Genetics and proteomics: deciphering gene association studies in critical illness.