Literature DB >> 18388019

The use of stem cells in the treatment of inoperable limb ischemia.

William H Pearce1, Richard Burt, Heron E Rodriguez.   

Abstract

Autologous stem cell-based therapy offers many advantages over other nonsurgical treatments of peripheral arterial disease. Transplant stem cells are a renewable source of multiple cytokines and growth factors. Autologous adult stem cells are not rejected and do not form teratomas. Early preliminary results indicate that adult stem cell therapy is safe and effective in patients with critical limb ischemia.

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Year:  2008        PMID： 18388019     DOI： 10.1177/1531003507313300

Source DB:  PubMed          Journal:  Perspect Vasc Surg Endovasc Ther        ISSN： 1521-5768


  2 in total

1.  X-ray-visible microcapsules containing mesenchymal stem cells improve hind limb perfusion in a rabbit model of peripheral arterial disease.

Authors:  Dorota A Kedziorek; Lawrence V Hofmann; Yingli Fu; Wesley D Gilson; Kenyatta M Cosby; Bernard Kohl; Brad P Barnett; Brian W Simons; Piotr Walczak; Jeff W M Bulte; Kathleen Gabrielson; Dara L Kraitchman
Journal:  Stem Cells       Date:  2012-06       Impact factor: 6.277

2.  A double blind randomized placebo controlled phase I/II study assessing the safety and efficacy of allogeneic bone marrow derived mesenchymal stem cell in critical limb ischemia.

Authors:  Pawan K Gupta; Anoop Chullikana; Rajiv Parakh; Sanjay Desai; Anjan Das; Sanjay Gottipamula; Sagar Krishnamurthy; Naveen Anthony; Arun Pherwani; Anish S Majumdar
Journal:  J Transl Med       Date:  2013-06-10       Impact factor: 5.531
  2 in total

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