Literature DB >> 18387471

Age-related differences in diagnosis and morbidity of intestinal malrotation.

Emily T Durkin1, Dennis P Lund, Aimen F Shaaban, Michael J Schurr, Sharon M Weber.   

Abstract

BACKGROUND: Intestinal malrotation in adulthood may present with a variety of chronic symptoms. Surgical intervention frequently leads to other complications in these patients. We hypothesized that the chronic nature of malrotation in adults could cause a delay in diagnosis and increased perioperative complications. STUDY
DESIGN: All patients diagnosed with intestinal malrotation from July 2002 through July 2006 were included. IRB approval was obtained. Outcomes in patients less than 16 years of age were compared with outcomes from those older than 16. Presenting symptoms, initial diagnosis, results of imaging data, and time to diagnosis were evaluated. Surgical management, resulting complications, and rate of reoperation were analyzed.
RESULTS: Twenty-four patients with intestinal malrotation were identified (age range, 10 days to 89 years old; 10 adults, 14 children). Seventy percent of adults experienced chronic symptoms for 6 months or more before the diagnosis of malrotation was made (children, 14%, p = 0.017). No patients in the adult group were initially diagnosed with malrotation, although 57% of children were correctly diagnosed at the time of presentation of symptoms (p=0.006). Postoperative complications occurred in 60% of adults, but in only 29% of children, though this did not reach significance (p=0.211). Forty percent of adult patients required reoperation (p=0.020).
CONCLUSIONS: Intestinal malrotation in adults is often associated with a delay in diagnosis and increased morbidity. Enhanced awareness of this entity in adults may enhance patient counseling and improve therapeutic outcomes in these patients.

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Mesh:

Year:  2008        PMID: 18387471     DOI: 10.1016/j.jamcollsurg.2007.11.020

Source DB:  PubMed          Journal:  J Am Coll Surg        ISSN: 1072-7515            Impact factor:   6.113


  32 in total

1.  Intestinal malrotation associated with colon cancer in an adult: report of a case.

Authors:  Pei-Tu Ren; Bao-Chun Lu
Journal:  Surg Today       Date:  2009-06-28       Impact factor: 2.549

2.  Adult intestinal malrotation: when things turn the wrong way.

Authors:  Owen P Palmer; Horace H Rhee; Walter G Park; Brendan C Visser
Journal:  Dig Dis Sci       Date:  2011-07-30       Impact factor: 3.199

3.  Malrotation Correction in the Adult Population.

Authors:  Joseph G Brungardt; Sean C Liebscher; Kurt P Schropp
Journal:  World J Surg       Date:  2020-09-25       Impact factor: 3.352

Review 4.  Adult Presentations of Congenital Midgut Malrotation: A Systematic Review.

Authors:  Jonathan J Neville; Jack Gallagher; Anuja Mitra; Hemant Sheth
Journal:  World J Surg       Date:  2020-06       Impact factor: 3.352

5.  Laparoscopic versus open Ladd's procedure for intestinal malrotation in adults.

Authors:  Lane L Frasier; Glen Leverson; Ankush Gosain; Jacob Greenberg
Journal:  Surg Endosc       Date:  2014-10-08       Impact factor: 4.584

6.  Subhepatic caecal tumour in an adult with intestinal malrotation.

Authors:  Joseph Michael Norris; Desmond Owusu; Ammar Adel Abdullah; Kanapathippillai Rajaratnam
Journal:  BMJ Case Rep       Date:  2014-10-29

Review 7.  Small Bowel Congenital Anomalies: a Review and Update.

Authors:  Grant Morris; Alfred Kennedy; William Cochran
Journal:  Curr Gastroenterol Rep       Date:  2016-04

8.  Laparoscopic surgery for the ascending colon cancer associated with malrotation of the midgut.

Authors:  Yasumitsu Hirano; Masakazu Hattori; Daisuke Yagi; Kazuya Maeda; Kenji Douden; Yasuo Hashizume
Journal:  Indian J Surg       Date:  2011-10-19       Impact factor: 0.656

9.  Soft tissue case 61.

Authors:  Lisa Aird; Pari Tiwari; Carl J Brown
Journal:  Can J Surg       Date:  2009-08       Impact factor: 2.089

Review 10.  Malrotation of the Intestine in Adult and Colorectal Cancer.

Authors:  Dipankar Ray; Mitsuaki Morimoto
Journal:  Indian J Surg       Date:  2015-09-04       Impact factor: 0.656

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