Literature DB >> 18386223

Membrane proteins as diagnostic biomarkers and targets for new therapies.

Djuro Josic1, James G Clifton, Spomenka Kovac, Douglas C Hixson.   

Abstract

Membrane proteins, especially plasma membrane proteins, form one of the most interesting classes of proteins among disease biomarker candidates. Because of their localization on the surface of cells and organelles, membrane proteins also represent potential drug targets. In this review, developments in the characterization of membrane proteins and their role in the treatment of disease, in particular cancer treatment, are presented.

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Year:  2008        PMID: 18386223

Source DB:  PubMed          Journal:  Curr Opin Mol Ther        ISSN: 1464-8431


  10 in total

1.  Upregulation of MARCKS in kidney cancer and its potential as a therapeutic target.

Authors:  C-H Chen; L W R Fong; E Yu; R Wu; J F Trott; R H Weiss
Journal:  Oncogene       Date:  2017-02-06       Impact factor: 9.867

2.  Isolation of Single-Domain Antibodies to Transmembrane Proteins Using Magnetized Yeast Cell Targets.

Authors:  Kaitlyn Bacon; Stefano Menegatti; Balaji M Rao
Journal:  Methods Mol Biol       Date:  2022

3.  Towards a membrane proteome in Drosophila: a method for the isolation of plasma membrane.

Authors:  Mansi R Khanna; Bruce A Stanley; Graham H Thomas
Journal:  BMC Genomics       Date:  2010-05-12       Impact factor: 3.969

4.  Comparative Membranome expression analysis in primary tumors and derived cell lines.

Authors:  Paolo Uva; Armin Lahm; Andrea Sbardellati; Anita Grigoriadis; Andrew Tutt; Emanuele de Rinaldis
Journal:  PLoS One       Date:  2010-07-23       Impact factor: 3.240

5.  Quantitative label-free proteomic analysis of human urine to identify novel candidate protein biomarkers for schistosomiasis.

Authors:  Olugbenga Samson Onile; Bridget Calder; Nelson C Soares; Chiaka I Anumudu; Jonathan M Blackburn
Journal:  PLoS Negl Trop Dis       Date:  2017-11-08

6.  Molecular phenotyping of the surfaceome of migratory chondroprogenitors and mesenchymal stem cells using biotinylation, glycocapture and quantitative LC-MS/MS proteomic analysis.

Authors:  Csaba Matta; David J Boocock; Christopher R Fellows; Nicolai Miosge; James E Dixon; Susan Liddell; Julia Smith; Ali Mobasheri
Journal:  Sci Rep       Date:  2019-06-21       Impact factor: 4.379

7.  TJP1, a Membrane-Expressed Protein, is a Potential Therapeutic and Prognostic Target for Lung Cancer.

Authors:  Junyi Pu; Tao Ai; Weining Weng; Lijun Wang; Yuan Yang; Linjie Ma; Zhiping Hu; Xun Meng
Journal:  Technol Cancer Res Treat       Date:  2022 Jan-Dec

8.  iTRAQ-based proteomics profiling reveals increased metabolic activity and cellular cross-talk in angiogenic compared with invasive glioblastoma phenotype.

Authors:  Uros Rajcevic; Kjell Petersen; Jaco C Knol; Maarten Loos; Sébastien Bougnaud; Oleg Klychnikov; Ka Wan Li; Thang V Pham; Jian Wang; Hrvoje Miletic; Zhao Peng; Rolf Bjerkvig; Connie R Jimenez; Simone P Niclou
Journal:  Mol Cell Proteomics       Date:  2009-08-12       Impact factor: 5.911

9.  SNPs altering ammonium transport activity of human Rhesus factors characterized by a yeast-based functional assay.

Authors:  Aude Deschuyteneer; Mélanie Boeckstaens; Christelle De Mees; Pascale Van Vooren; René Wintjens; Anna Maria Marini
Journal:  PLoS One       Date:  2013-08-13       Impact factor: 3.240

10.  Oligonucleotide aptamers: new tools for targeted cancer therapy.

Authors:  Hongguang Sun; Xun Zhu; Patrick Y Lu; Roberto R Rosato; Wen Tan; Youli Zu
Journal:  Mol Ther Nucleic Acids       Date:  2014-08-05       Impact factor: 10.183

  10 in total

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