Literature DB >> 18385225

The burden of asymptomatic sexually transmitted infections among men in Carletonville, South Africa: implications for syndromic management.

D A Lewis1, C Pillay, O Mohlamonyane, A Vezi, S Mbabela, Y Mzaidume, F Radebe.   

Abstract

OBJECTIVES: To determine the prevalence of sexually transmitted infections (STI) and HIV among men attending an outreach STI/HIV screening service in informal settlements in South Africa over a 3-month period.
METHODS: A mobile clinic van was utilised to offer men: (1) urine screening for gonorrhoea, trichomoniasis, chlamydial and Mycoplasma genitalium infections; (2) serological screening for syphilis and herpes simplex virus type 2 (HSV-2); (3) on-site HIV voluntary counselling and testing. Urethritis pathogens were detected by molecular methods. HIV serostatus was determined using rapid tests. Demographic, sexual behaviour and clinical data were recorded on a nurse-administered questionnaire. Statistical analysis utilised the chi(2) test.
RESULTS: 309 men attended the service; 304 (98%) requested serological screening for syphilis and HSV-2, 301 (97%) underwent urine-based screening for urethritis pathogens and 269 (87%) had an HIV test. Over 90% of men were asymptomatic for STI. Gonorrhoea was more prevalent in the symptomatic group (p<0.001); there were no significant differences in the prevalence of other urethritis pathogens between the groups. The total number of infections with each urethritis pathogen was highest in the asymptomatic group with twice as much gonorrhoea, 25 times as much chlamydial infection, six times as much trichomoniasis and nine times as much M genitalium infection compared with the symptomatic group. The overall HIV prevalence among clinic attendees was 29.7%.
CONCLUSIONS: The uptake of both STI and HIV testing was high among men attending the service. The relatively high burden of both STI and HIV among the male clinic attendees has implications for the transmission of HIV.

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Year:  2008        PMID: 18385225     DOI: 10.1136/sti.2008.029751

Source DB:  PubMed          Journal:  Sex Transm Infect        ISSN: 1368-4973            Impact factor:   3.519


  10 in total

1.  The effect of medical male circumcision on urogenital Mycoplasma genitalium among men in Kisumu, Kenya.

Authors:  Supriya D Mehta; Charlotte Gaydos; Ian Maclean; Elijah Odoyo-June; Stephen Moses; Lawrence Agunda; Nicole Quinn; Robert C Bailey
Journal:  Sex Transm Dis       Date:  2012-04       Impact factor: 2.830

2.  Sexual and reproductive health behaviors of undocumented migrants in Geneva: a cross sectional study.

Authors:  Paul Sebo; Yves Jackson; Dagmar M Haller; Jean-Michel Gaspoz; Hans Wolff
Journal:  J Immigr Minor Health       Date:  2011-06

3.  Performance and comparison of self-reported STI symptoms among high-risk populations - MSM, sex workers, persons living with HIV/AIDS - in El Salvador.

Authors:  Neha S Shah; Evelyn Kim; Flor de Maria Hernández Ayala; Maria Elena Guardado Escobar; Ana Isabel Nieto; Andrea A Kim; Gabriela Paz-Bailey
Journal:  Int J STD AIDS       Date:  2014-03-10       Impact factor: 1.359

4.  Partner notification and treatment outcomes among South African adolescents and young adults diagnosed with a sexually transmitted infection via laboratory-based screening.

Authors:  Pooja Chitneni; Mags Beksinska; Janan J Dietrich; Manjeetha Jaggernath; Kalysha Closson; Patricia Smith; David A Lewis; Lynn T Matthews; Jenni Smit; Thumbi Ndung'u; Mark Brockman; Glenda Gray; Angela Kaida
Journal:  Int J STD AIDS       Date:  2020-05-13       Impact factor: 1.359

5.  The incidence and correlates of symptomatic and asymptomatic Chlamydia trachomatis and Neisseria gonorrhoeae infections in selected populations in five countries.

Authors:  Roger Detels; Annette M Green; Jeffrey D Klausner; David Katzenstein; Charlotte Gaydos; H Hunter Handsfield; Willo Pequegnat; Kenneth Mayer; Tyler D Hartwell; Thomas C Quinn
Journal:  Sex Transm Dis       Date:  2011-06       Impact factor: 2.830

6.  Should we screen for the sexually-transmitted infection Mycoplasma genitalium? Evidence synthesis using a transmission-dynamic model.

Authors:  Ruthie Birger; John Saunders; Claudia Estcourt; Andrew John Sutton; Catherine H Mercer; Tracy Roberts; Peter J White
Journal:  Sci Rep       Date:  2017-11-23       Impact factor: 4.379

7.  Antimicrobial susceptibility profile of Gonococcal isolates obtained from men presenting with urethral discharge in Addis Ababa, Ethiopia: Implications for national syndromic treatment guideline.

Authors:  Surafel Fentaw; Rajiha Abubeker; Negga Asamene; Meseret Assefa; Yonas Bekele; Eyasu Tigabu
Journal:  PLoS One       Date:  2020-06-01       Impact factor: 3.240

Review 8.  Outreach for chlamydia and gonorrhoea screening: a systematic review of strategies and outcomes.

Authors:  Belinda Hengel; Muhammad S Jamil; Jacqueline K Mein; Lisa Maher; John M Kaldor; Rebecca J Guy
Journal:  BMC Public Health       Date:  2013-11-04       Impact factor: 3.295

9.  Measuring underreporting and under-ascertainment in infectious disease datasets: a comparison of methods.

Authors:  Cheryl L Gibbons; Marie-Josée J Mangen; Dietrich Plass; Arie H Havelaar; Russell John Brooke; Piotr Kramarz; Karen L Peterson; Anke L Stuurman; Alessandro Cassini; Eric M Fèvre; Mirjam E E Kretzschmar
Journal:  BMC Public Health       Date:  2014-02-11       Impact factor: 3.295

10.  A high burden of asymptomatic genital tract infections undermines the syndromic management approach among adolescents and young adults in South Africa: implications for HIV prevention efforts.

Authors:  Angela Kaida; Janan J Dietrich; Fatima Laher; Mags Beksinska; Manjeetha Jaggernath; Megan Bardsley; Patricia Smith; Laura Cotton; Pooja Chitneni; Kalysha Closson; David A Lewis; Jenni A Smit; Thumbi Ndung'u; Mark Brockman; Glenda Gray
Journal:  BMC Infect Dis       Date:  2018-10-03       Impact factor: 3.090

  10 in total

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