Literature DB >> 18383487

Beta-lactones as privileged structures for the active-site labeling of versatile bacterial enzyme classes.

Thomas Böttcher1, Stephan A Sieber.   

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Year:  2008        PMID： 18383487     DOI： 10.1002/anie.200705768

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  46 in total

1.  Competitive activity-based protein profiling identifies aza-β-lactams as a versatile chemotype for serine hydrolase inhibition.

Authors:  Andrea M Zuhl; Justin T Mohr; Daniel A Bachovchin; Sherry Niessen; Ku-Lung Hsu; Jacob M Berlin; Maximilian Dochnahl; María P López-Alberca; Gregory C Fu; Benjamin F Cravatt
Journal:  J Am Chem Soc       Date:  2012-03-08       Impact factor: 15.419

2.  N-activated β-lactams as versatile reagents for acyl carrier protein labeling.

Authors:  Gitanjeli Prasad; Jon W Amoroso; Lawrence S Borketey; Nathan A Schnarr
Journal:  Org Biomol Chem       Date:  2012-01-31       Impact factor: 3.876

3.  Strategies for discovering and derisking covalent, irreversible enzyme inhibitors.

Authors:  Douglas S Johnson; Eranthie Weerapana; Benjamin F Cravatt
Journal:  Future Med Chem       Date:  2010-06       Impact factor: 3.808

4.  Diastereoselective, three-component cascade synthesis of tetrahydrofurans and tetrahydropyrans employing the tandem Mukaiyama aldol-lactonization process.

Authors:  T Andrew Mitchell; Cunxiang Zhao; Daniel Romo
Journal:  J Org Chem       Date:  2008-12-19       Impact factor: 4.354

5.  Identification of selective covalent inhibitors of platelet activating factor acetylhydrolase 1B2 from the screening of an oxadiazolone-capped peptoid-azapeptoid hybrid library.

Authors:  Bani Kanta Sarma; Xiaodan Liu; Thomas Kodadek
Journal:  Bioorg Med Chem       Date:  2016-04-23       Impact factor: 3.641

6.  Active site labeling of fatty acid and polyketide acyl-carrier protein transacylases.

Authors:  Tony D Davis; Jennifer M Michaud; Michael D Burkart
Journal:  Org Biomol Chem       Date:  2019-05-15       Impact factor: 3.876

7.  Design of Benzoxathiazin-3-one 1,1-Dioxides as a New Class of Irreversible Serine Hydrolase Inhibitors: Discovery of a Uniquely Selective PNPLA4 Inhibitor.

Authors:  Anne F Kornahrens; Armand B Cognetta; Daniel M Brody; Megan L Matthews; Benjamin F Cravatt; Dale L Boger
Journal:  J Am Chem Soc       Date:  2017-05-12       Impact factor: 15.419

Review 8.  Bacterial proteases, untapped antimicrobial drug targets.

Authors:  Elizabeth Culp; Gerard D Wright
Journal:  J Antibiot (Tokyo)       Date:  2016-11-30       Impact factor: 2.649

9.  Reversible inhibition of the ClpP protease via an N-terminal conformational switch.

Authors:  Siavash Vahidi; Zev A Ripstein; Massimiliano Bonomi; Tairan Yuwen; Mark F Mabanglo; Jordan B Juravsky; Kamran Rizzolo; Algirdas Velyvis; Walid A Houry; Michele Vendruscolo; John L Rubinstein; Lewis E Kay
Journal:  Proc Natl Acad Sci U S A       Date:  2018-06-25       Impact factor: 11.205

Review 10.  Using small molecules to dissect mechanisms of microbial pathogenesis.

Authors:  Aaron W Puri; Matthew Bogyo
Journal:  ACS Chem Biol       Date:  2009-08-21       Impact factor: 5.100
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