Literature DB >> 1838215

Selenoprotein synthesis: an expansion of the genetic code.

A Böck1, K Forchhammer, J Heider, C Baron.   

Abstract

A number of enzymes employ the unusual amino acid selenocysteine as part of their active site because of its high chemical reactivity. Selenocysteine is incorporated into these proteins co-translationally: biosynthesis occurs on a specific tRNA and insertion into a growing polypeptide is directed by a UGA codon in the mRNA. In E. coli, this requires a specific translation factor. Selenocysteine thus represents a unique expansion of the genetic code.

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Year:  1991        PMID： 1838215     DOI： 10.1016/0968-0004(91)90180-4

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN： 0968-0004            Impact factor:   13.807


  92 in total

1.  A dynamic competition between release factor 2 and the tRNA(Sec) decoding UGA at the recoding site of Escherichia coli formate dehydrogenase H.

Authors:  J B Mansell; D Guévremont; E S Poole; W P Tate
Journal:  EMBO J       Date:  2001-12-17       Impact factor: 11.598

Review 2.  How selenium has altered our understanding of the genetic code.

Authors:  Dolph L Hatfield; Vadim N Gladyshev
Journal:  Mol Cell Biol       Date:  2002-06       Impact factor: 4.272

3.  Isolation and characterization of cDNA encoding the antigenic protein of the human tRNP(Ser)Sec complex recognized by autoantibodies from patients withtype-1 autoimmune hepatitis.

Authors:  M Costa; J L Rodríguez-Sánchez; A J Czaja; C Gelpí
Journal:  Clin Exp Immunol       Date:  2000-08       Impact factor: 4.330

4.  pGp as the main product of bovine tRNA kinase.

Authors:  Takaharu Mizutani; Takashi Osaka; Yuko Ito; Masanobu Kanou; Toru Usui; Yumiko Sone; Tsuyoshi Totsuka
Journal:  Mol Biol Rep       Date:  2002-09       Impact factor: 2.316

5.  Identification of the major soluble cuticular glycoprotein of lymphatic filarial nematode parasites (gp29) as a secretory homolog of glutathione peroxidase.

Authors:  E Cookson; M L Blaxter; M E Selkirk
Journal:  Proc Natl Acad Sci U S A       Date:  1992-07-01       Impact factor: 11.205

6.  Evolution of the genetic triplet code via two types of doublet codons.

Authors:  Huan-Lin Wu; Stefan Bagby; Jean M H van den Elsen
Journal:  J Mol Evol       Date:  2005-07-19       Impact factor: 2.395

7.  Characterization of a selenate-resistant Arabidopsis mutant. Root growth as a potential target for selenate toxicity.

Authors:  Elie El Kassis; Nicole Cathala; Hatem Rouached; Pierre Fourcroy; Pierre Berthomieu; Norman Terry; Jean-Claude Davidian
Journal:  Plant Physiol       Date:  2007-01-05       Impact factor: 8.340

8.  Enhanced selenium tolerance and accumulation in transgenic Arabidopsis expressing a mouse selenocysteine lyase.

Authors:  Marinus Pilon; Jennifer D Owen; Gulnara F Garifullina; Tatsuo Kurihara; Hisaaki Mihara; Nobuyoshi Esaki; Elizabeth A H Pilon-Smits
Journal:  Plant Physiol       Date:  2003-03       Impact factor: 8.340

9.  Expression of fluorescent cyclotides using protein trans-splicing for easy monitoring of cyclotide-protein interactions.

Authors:  Krishnappa Jagadish; Radhika Borra; Vanessa Lacey; Subhabrata Majumder; Alexander Shekhtman; Lei Wang; Julio A Camarero
Journal:  Angew Chem Int Ed Engl       Date:  2013-01-15       Impact factor: 15.336

10.  The physiology and habitat of the last universal common ancestor.

Authors:  Madeline C Weiss; Filipa L Sousa; Natalia Mrnjavac; Sinje Neukirchen; Mayo Roettger; Shijulal Nelson-Sathi; William F Martin
Journal:  Nat Microbiol       Date:  2016-07-25       Impact factor: 17.745
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