Literature DB >> 18381742

Ring-closing metathesis: novel routes to aromatic heterocycles.

Timothy J Donohoe1, Lisa P Fishlock, Panayiotis A Procopiou.   

Abstract

Olefin metathesis has been established as an important and general reaction in synthetic organic chemistry. Recently, it has attracted interest as a powerful tool for the construction of aromatic heterocycles. The importance of heteroaromatic motifs in medicinal chemistry and biology, as well as the efficiency and wealth of metathesis transformations, have resulted in significant success in this rapidly developing area.

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Year:  2008        PMID： 18381742     DOI： 10.1002/chem.200800130

Source DB:  PubMed          Journal:  Chemistry        ISSN： 0947-6539            Impact factor:   5.236


  9 in total

1.  Enol ethers as substrates for efficient Z- and enantioselective ring-opening/cross-metathesis reactions promoted by stereogenic-at-Mo complexes: utility in chemical synthesis and mechanistic attributes.

Authors:  Miao Yu; Ismail Ibrahem; Masayuki Hasegawa; Richard R Schrock; Amir H Hoveyda
Journal:  J Am Chem Soc       Date:  2012-01-24       Impact factor: 15.419

Review 2.  Transition metal-mediated synthesis of monocyclic aromatic heterocycles.

Authors:  Anton V Gulevich; Alexander S Dudnik; Natalia Chernyak; Vladimir Gevorgyan
Journal:  Chem Rev       Date:  2013-01-10       Impact factor: 60.622

3.  Olefin cross-metathesis-based approaches to furans: procedures for the preparation of di- and trisubstituted variants.

Authors:  Timothy J Donohoe; John F Bower; José A Basutto
Journal:  Nat Protoc       Date:  2010-12-02       Impact factor: 13.491

4.  An expedient route to substituted furans via olefin cross-metathesis.

Authors:  Timothy J Donohoe; John F Bower
Journal:  Proc Natl Acad Sci U S A       Date:  2010-02-08       Impact factor: 11.205

Review 5.  Alkynoates as Versatile and Powerful Chemical Tools for the Rapid Assembly of Diverse Heterocycles under Transition-Metal Catalysis: Recent Developments and Challenges.

Authors:  Imtiaz Khan; Aliya Ibrar; Sumera Zaib
Journal:  Top Curr Chem (Cham)       Date:  2021-01-05

6.  Efficient and selective formation of macrocyclic disubstituted Z alkenes by ring-closing metathesis (RCM) reactions catalyzed by Mo- or W-based monoaryloxide pyrrolide (MAP) complexes: applications to total syntheses of epilachnene, yuzu lactone, ambrettolide, epothilone C, and nakadomarin A.

Authors:  Chenbo Wang; Miao Yu; Andrew F Kyle; Pavol Jakubec; Darren J Dixon; Richard R Schrock; Amir H Hoveyda
Journal:  Chemistry       Date:  2013-01-23       Impact factor: 5.236

7.  Organic-inorganic hybrid silica material derived from a monosilylated Grubbs-Hoveyda ruthenium carbene as a recyclable metathesis catalyst.

Authors:  Guadalupe Borja; Roser Pleixats; Ramón Alibés; Xavier Cattoën; Michel Wong Chi Man
Journal:  Molecules       Date:  2010-08-23       Impact factor: 4.411

8.  De novo synthesis of multisubstituted aryl amines using alkene cross metathesis.

Authors:  Matthew R Tatton; Iain Simpson; Timothy J Donohoe
Journal:  Org Lett       Date:  2014-03-19       Impact factor: 6.005

9.  Z-Selective olefin metathesis on peptides: investigation of side-chain influence, preorganization, and guidelines in substrate selection.

Authors:  Shane L Mangold; Daniel J O'Leary; Robert H Grubbs
Journal:  J Am Chem Soc       Date:  2014-08-20       Impact factor: 15.419
  9 in total

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