| Literature DB >> 18381085 |
Abstract
MicroRNAs (miRNAs) are a class of non-coding RNAs involved in post-transcriptional gene silencing. A small number of striated muscle-specific miRNAs have been identified and shown to have an important role in myogenesis, embryonic muscle growth and cardiac function and hypertrophy. One of these myomiRs (myo=muscle+miR=miRNA), miR-206, is unique in that it is only expressed in skeletal muscle. The purpose of this review is to discuss what is currently known about miR-206 and its function in myogenesis as well as propose potential new roles for miR-206 in skeletal muscle biology. The review is also intended to serve as a comprehensive resource for miR-206 with the hope of encouraging further research on the role of miR-206 in skeletal muscle.Entities:
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Year: 2008 PMID： 18381085 PMCID： PMC2656394 DOI： 10.1016/j.bbagrm.2008.03.001
Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002