Literature DB >> 18380830

Unusual solitary metastasis of the ciliary body in renal cell carcinoma.

Vito Mancini1, Michele Battaglia, Giuseppe Lucarelli, Vito Di Lorenzo, Pasquale Ditonno, Carlo Bettocchi, Francesco Paolo Selvaggi.   

Abstract

Renal cell carcinoma (RCC) usually metastasizes to the lung, liver, bone; ocular metastasis is uncommon. We describe a rare case of metachronous ciliary RCC metastasis in a 42-year-old man who had undergone left radical nephrectomy for conventional RCC (pT3aN0M0, G2 Fuhrman) 6 years earlier. Solitary metastasis of the left eye presented with inflammatory symptoms, but examination of the fundus and bulbar ultrasound revealed a small mass of the ciliary body. Initial radiotherapy was unsuccessful and definitive treatment consisted of ocular enucleation with radical result and no further evidence of local and distant disease. Ocular metastasis of RCC is rare, can appear years after treating the primary tumor and should not be excluded in RCC follow-up. As for other RCC solitary metastasis, the best option remains the radical surgical approach.

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Year:  2008        PMID: 18380830     DOI: 10.1111/j.1442-2042.2008.02004.x

Source DB:  PubMed          Journal:  Int J Urol        ISSN: 0919-8172            Impact factor:   3.369


  7 in total

1.  Renal cell carcinoma metastasis to the ciliary body responds to proton beam radiotherapy: a case report.

Authors:  Tarek Alasil; Bahram Khazai; Lilia Loredo; Michael E Rauser
Journal:  J Med Case Rep       Date:  2011-08-03

2.  Genitourinary malignancy presenting as an ocular metastasis: A case report and review of the literature.

Authors:  Shilo Lefresne; Alysa Fairchild; Royce Johnson; Jean Deschenes; Laurie Russell; John Pederson
Journal:  Can Urol Assoc J       Date:  2012-04       Impact factor: 1.862

3.  Renal cell carcinoma with unusual metastasis to the small intestine manifesting as extensive polyposis: successful management with intraoperative therapeutic endoscopy.

Authors:  Pankaj G Vashi; Elham Abboud; Digant Gupta
Journal:  Case Rep Gastroenterol       Date:  2011-08-22

4.  Metachronous bladder metastases from renal cell carcinoma: a case report and review of the literature.

Authors:  S Melegari; G Albo; B Rocco; F Verweij; M Abbinante; O de Cobelli
Journal:  Ecancermedicalscience       Date:  2010-03-18

5.  Ciliary body metastasis from renal cell carcinoma successfully treated with intravitreal bevacizumab.

Authors:  Margaret Wong; W Barry Lee; Robert L Halpern; James H Frank
Journal:  Am J Ophthalmol Case Rep       Date:  2017-03-14

6.  Neuron-Specific Enolase and Hemoglobin as Risk Factors of Intraocular Metastasis in Patients with Renal Cell Carcinoma.

Authors:  Qiu-Yu Li; Ting Su; Wen-Qing Shi; Jian-Wen Fang; Meng-Yao Zhang; Qian-Hui Xu; Rong-Bin Liang; Qian-Min Ge; Biao Li; Yi Shao
Journal:  Dis Markers       Date:  2022-04-23       Impact factor: 3.434

Review 7.  Metachronous bladder metastases of a type 2 papillary renal cell carcinoma: a case report and review of the literature.

Authors:  D G V D Seneth Gajasinghe; Ishra Nazeer; Hansika P Maddumage; Chrysantha Perera; Anuruddha M Abeygunasekera
Journal:  World J Surg Oncol       Date:  2016-08-22       Impact factor: 2.754

  7 in total

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