Literature DB >> 1838044

A population-based study of the incidence of complications associated with type 2 diabetes in the elderly.

D L Cohen1, H A Neil, M Thorogood, J I Mann.   

Abstract

One hundred and eighty-eight known Type 2 diabetic patients aged over 60 years identified by a geographically based survey of a population of 40,076 were followed for a median of 6 years to determine the incidence of various complications. There were 63 deaths and two patients were lost to follow-up. The presence of complications was determined using a structured questionnaire and clinical examination. Incidence rates of ischaemic heart disease, stroke, and peripheral vascular disease (PVD) were 56 (95% CI 41-75), 22 (13-35), and 146 (117-174) 1000-person-years-1 of follow-up, respectively. Rates of stroke and PVD rose significantly with age. Retinopathy occurred at a rate of 60 (42-83) 1000-person-years-1 and cataract at 29 (17-46) 1000-person-years-1 although visual acuity in survivors did not deteriorate overall, probably reflecting the high mortality associated with cataract. The rate of proteinuria (albumin concentration greater than 300 mg l-1) was 19 (9-34) 1000-person-years-1. Incidence rates were unrelated to sex or duration of diabetes. Diabetes is associated with a continuing incidence of complications into old age. Adequate facilities are required to assess and treat the resulting morbidity in a population with an increasing proportion of elderly people.

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Mesh:

Year:  1991        PMID: 1838044     DOI: 10.1111/j.1464-5491.1991.tb01532.x

Source DB:  PubMed          Journal:  Diabet Med        ISSN: 0742-3071            Impact factor:   4.359


  6 in total

1.  Prevalence of self-rated visual impairment among adults with diabetes.

Authors:  J B Saaddine; K M Narayan; M M Engelgau; R E Aubert; R Klein; G L Beckles
Journal:  Am J Public Health       Date:  1999-08       Impact factor: 9.308

2.  Diabetes mellitus.

Authors:  M Cottee; I R Hastie
Journal:  Postgrad Med J       Date:  1995-05       Impact factor: 2.401

3.  Prevalence and forms of neuropathic morbidity in 800 diabetics.

Authors:  J A O'Hare; F Abuaisha; M Geoghegan
Journal:  Ir J Med Sci       Date:  1994-03       Impact factor: 1.568

Review 4.  New approaches to treating type 2 diabetes mellitus in the elderly: role of incretin therapies.

Authors:  Angela M Abbatecola; Stefania Maggi; Giuseppe Paolisso
Journal:  Drugs Aging       Date:  2008       Impact factor: 3.923

5.  Presence of diabetes related complication at the time of NIDDM diagnosis: an important prognostic factor.

Authors:  A Ruigómez; L A García Rodríguez
Journal:  Eur J Epidemiol       Date:  1998-07       Impact factor: 8.082

6.  Long-term instability of fasting plasma glucose predicts mortality in elderly NIDDM patients: the Verona Diabetes Study.

Authors:  M Muggeo; G Verlato; E Bonora; F Ciani; P Moghetti; R Eastman; G Crepaldi; R de Marco
Journal:  Diabetologia       Date:  1995-06       Impact factor: 10.122

  6 in total

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