Literature DB >> 18380439

Synthesis of homochiral dihydroxy-4-nitroisoxazolines via one-pot asymmetric dihydroxylation-reduction.

Mauro F A Adamo1, Murali Nagabelli.   

Abstract

Herein we report a one-pot procedure to prepare a family of homochiral dihydroxy-4-nitroisoxazolines 3. This new methodology affords the title compounds in good yields, excellent enantiopurity, and without the use of chromatography.

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Year:  2008        PMID： 18380439     DOI： 10.1021/ol800397z

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  3 in total

1.  Diastereoselective additive trifluoromethylation/halogenation of isoxazole triflones: synthesis of all-carbon-functionalized trifluoromethyl isoxazoline triflones.

Authors:  Hiroyuki Kawai; Yutaka Sugita; Etsuko Tokunaga; Hiroyasu Sato; Motoo Shiro; Norio Shibata
Journal:  ChemistryOpen       Date:  2014-02-13       Impact factor: 2.911

2.  Organocatalytic one-pot 1,4-/1,6-/1,2-addition sequence for the stereocontrolled formation of six consecutive stereocenters.

Authors:  Pankaj Chauhan; Suruchi Mahajan; Gerhard Raabe; Dieter Enders
Journal:  Chem Commun (Camb)       Date:  2015-02-11       Impact factor: 6.222

3.  Allylic-Allylic Alkylation with 3,5-Dimethyl-4-nitroisoxazole: A Route to Dicarboxylic Acid Derivatives.

Authors:  Dorota Kowalczyk-Dworak; Marcin Kwit; Łukasz Albrecht
Journal:  J Org Chem       Date:  2020-02-20       Impact factor: 4.354
  3 in total

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