Literature DB >> 18379594

Neurogenesis directed by Sirt1.

Sergiy Libert1, Dena Cohen, Leonard Guarente.   

Abstract

Differentiation of neuronal stem cells into astrocytes or neurons is important in maintaining brain function. Oxidative stress and inflammation are now shown to bias differentiation toward astrocytes by modulating activity of the anti-ageing gene Sirt1. These findings link a longevity gene to the activity of neuronal stem cells and their response to stress.

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Year:  2008        PMID： 18379594      PMCID： PMC2703710          DOI： 10.1038/ncb0408-373

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN： 1465-7392            Impact factor:   28.824


  9 in total

1.  Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction.

Authors:  Weiping Qin; Tianle Yang; Lap Ho; Zhong Zhao; Jun Wang; Linghong Chen; Wei Zhao; Meenakshisundaram Thiyagarajan; Donal MacGrogan; Joseph T Rodgers; Pere Puigserver; Junichi Sadoshima; Haiteng Deng; Steven Pedrini; Samuel Gandy; Anthony A Sauve; Giulio M Pasinetti
Journal:  J Biol Chem       Date:  2006-06-02       Impact factor: 5.157

2.  Sirt1 contributes critically to the redox-dependent fate of neural progenitors.

Authors:  Timour Prozorovski; Ulf Schulze-Topphoff; Robert Glumm; Jan Baumgart; Friederike Schröter; Olaf Ninnemann; Elise Siegert; Ivo Bendix; Oliver Brüstle; Robert Nitsch; Frauke Zipp; Orhan Aktas
Journal:  Nat Cell Biol       Date:  2008-03-16       Impact factor: 28.824

3.  SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}.

Authors:  Shino Nemoto; Maria M Fergusson; Toren Finkel
Journal:  J Biol Chem       Date:  2005-02-16       Impact factor: 5.157

4.  Regulation of Drosophila life span by olfaction and food-derived odors.

Authors:  Sergiy Libert; Jessica Zwiener; Xiaowen Chu; Wayne Vanvoorhies; Gregg Roman; Scott D Pletcher
Journal:  Science       Date:  2007-02-01       Impact factor: 47.728

5.  Negative control of p53 by Sir2alpha promotes cell survival under stress.

Authors:  J Luo; A Y Nikolaev; S Imai; D Chen; F Su; A Shiloh; L Guarente; W Gu
Journal:  Cell       Date:  2001-10-19       Impact factor: 41.582

6.  Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration.

Authors:  Toshiyuki Araki; Yo Sasaki; Jeffrey Milbrandt
Journal:  Science       Date:  2004-08-13       Impact factor: 47.728

7.  Two neurons mediate diet-restriction-induced longevity in C. elegans.

Authors:  Nicholas A Bishop; Leonard Guarente
Journal:  Nature       Date:  2007-05-31       Impact factor: 49.962

8.  SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis.

Authors:  Dohoon Kim; Minh Dang Nguyen; Matthew M Dobbin; Andre Fischer; Farahnaz Sananbenesi; Joseph T Rodgers; Ivana Delalle; Joseph A Baur; Guangchao Sui; Sean M Armour; Pere Puigserver; David A Sinclair; Li-Huei Tsai
Journal:  EMBO J       Date:  2007-06-21       Impact factor: 11.598

9.  SIRT1 deacetylates and positively regulates the nuclear receptor LXR.

Authors:  Xiaoling Li; Songwen Zhang; Gil Blander; Jeanette G Tse; Monty Krieger; Leonard Guarente
Journal:  Mol Cell       Date:  2007-10-12       Impact factor: 17.970
  9 in total
  20 in total

Review 1.  Senescence suppressors: their practical importance in replicative lifespan extension in stem cells.

Authors:  Eun Seong Hwang
Journal:  Cell Mol Life Sci       Date:  2014-07-23       Impact factor: 9.261

2.  Programmed hyperphagia in offspring of obese dams: Altered expression of hypothalamic nutrient sensors, neurogenic factors and epigenetic modulators.

Authors:  Mina Desai; Guang Han; Michael G Ross
Journal:  Appetite       Date:  2016-01-16       Impact factor: 3.868

Review 3.  Between destiny and disease: genetics and molecular pathways of human central nervous system aging.

Authors:  Christin Glorioso; Etienne Sibille
Journal:  Prog Neurobiol       Date:  2010-12-02       Impact factor: 11.685

4.  Long-term α1A-adrenergic receptor stimulation improves synaptic plasticity, cognitive function, mood, and longevity.

Authors:  Van A Doze; Robert S Papay; Brianna L Goldenstein; Manveen K Gupta; Katie M Collette; Brian W Nelson; Mariaha J Lyons; Bethany A Davis; Elizabeth J Luger; Sarah G Wood; James R Haselton; Paul C Simpson; Dianne M Perez
Journal:  Mol Pharmacol       Date:  2011-07-26       Impact factor: 4.436

Review 5.  The importance of NAD in multiple sclerosis.

Authors:  W Todd Penberthy; Ikuo Tsunoda
Journal:  Curr Pharm Des       Date:  2009       Impact factor: 3.116

6.  NAMPT is essential for the G-CSF-induced myeloid differentiation via a NAD(+)-sirtuin-1-dependent pathway.

Authors:  Julia Skokowa; Dan Lan; Basant Kumar Thakur; Fei Wang; Kshama Gupta; Gunnar Cario; Annette Müller Brechlin; Axel Schambach; Lars Hinrichsen; Gustav Meyer; Matthias Gaestel; Martin Stanulla; Qiang Tong; Karl Welte
Journal:  Nat Med       Date:  2009-02-01       Impact factor: 53.440

Review 7.  Mammalian sirtuins: biological insights and disease relevance.

Authors:  Marcia C Haigis; David A Sinclair
Journal:  Annu Rev Pathol       Date:  2010       Impact factor: 23.472

Review 8.  Nitrosative Stress, Hypernitrosylation, and Autoimmune Responses to Nitrosylated Proteins: New Pathways in Neuroprogressive Disorders Including Depression and Chronic Fatigue Syndrome.

Authors:  Gerwyn Morris; Michael Berk; Hans Klein; Ken Walder; Piotr Galecki; Michael Maes
Journal:  Mol Neurobiol       Date:  2016-06-23       Impact factor: 5.590

Review 9.  Does inflammation after stroke affect the developing brain differently than adult brain?

Authors:  Zinaida S Vexler; Midori A Yenari
Journal:  Dev Neurosci       Date:  2009-08-11       Impact factor: 2.984

10.  Programmed hyperphagia secondary to increased hypothalamic SIRT1.

Authors:  Mina Desai; Tie Li; Guang Han; Michael G Ross
Journal:  Brain Res       Date:  2014-09-22       Impact factor: 3.252
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