Literature DB >> 18379524

Connecting the interpodocyte slit diaphragm and actin dynamics: Emerging role for the nephrin signaling complex.

S Lehtonen1.   

Abstract

Uchida et al. show in this issue that in rat and human nephrosis, tyrosine phosphorylation of nephrin is reduced, and this is accompanied by a decrease in F-actin in glomeruli. This, together with previous studies, suggests that the nephrin protein complex is a signaling nexus that regulates actin dynamics in podocytes.

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Year:  2008        PMID： 18379524     DOI： 10.1038/ki.2008.69

Source DB:  PubMed          Journal:  Kidney Int        ISSN： 0085-2538            Impact factor:   10.612


  7 in total

Review 1.  Roles of adaptor proteins in podocyte biology.

Authors:  Tae-Sun Ha
Journal:  World J Nephrol       Date:  2013-02-06

2.  Actin-depolymerizing factor cofilin-1 is necessary in maintaining mature podocyte architecture.

Authors:  Puneet Garg; Rakesh Verma; Leslie Cook; Abdul Soofi; Madhusudan Venkatareddy; Britta George; Kensaku Mizuno; Christine Gurniak; Walter Witke; Lawrence B Holzman
Journal:  J Biol Chem       Date:  2010-05-15       Impact factor: 5.157

3.  Dexamethasone increases the phosphorylation of nephrin in cultured podocytes.

Authors:  Teiko Ohashi; Keiko Uchida; Shinichi Uchida; Sei Sasaki; Kosaku Nitta
Journal:  Clin Exp Nephrol       Date:  2011-06-23       Impact factor: 2.801

4.  Comparative effect of direct renin inhibition and AT1R blockade on glomerular filtration barrier injury in the transgenic Ren2 rat.

Authors:  Adam Whaley-Connell; Ravi Nistala; Javad Habibi; Melvin R Hayden; Rebecca I Schneider; Megan S Johnson; Roger Tilmon; Nathan Rehmer; Carlos M Ferrario; James R Sowers
Journal:  Am J Physiol Renal Physiol       Date:  2009-12-09

5.  Mineralocorticoid receptor antagonism attenuates glomerular filtration barrier remodeling in the transgenic Ren2 rat.

Authors:  Adam Whaley-Connell; Javad Habibi; Yongzhong Wei; Alex Gutweiler; Jessica Jellison; Charles E Wiedmeyer; Carlos M Ferrario; James R Sowers
Journal:  Am J Physiol Renal Physiol       Date:  2009-03-04

Review 6.  Genetics of nephrotic syndrome: new insights into molecules acting at the glomerular filtration barrier.

Authors:  Martin Zenker; Eduardo Machuca; Corinne Antignac
Journal:  J Mol Med (Berl)       Date:  2009-08-01       Impact factor: 4.599

7.  A role for nephrin, a renal protein, in vertebrate skeletal muscle cell fusion.

Authors:  Regina Lee Sohn; Ping Huang; Genri Kawahara; Matthew Mitchell; Jeffrey Guyon; Raghu Kalluri; Louis M Kunkel; Emanuela Gussoni
Journal:  Proc Natl Acad Sci U S A       Date:  2009-05-22       Impact factor: 11.205
  7 in total

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