| Literature DB >> 18378708 |
Nicole Cotroneo1, Robert Harris, Nancy Perlmutter, Terry Beveridge, Jared A Silverman.
Abstract
The ability of daptomycin to produce bactericidal activity against Staphylococcus aureus while causing negligible cell lysis has been demonstrated using electron microscopy and the membrane integrity probes calcein and ToPro3. The formation of aberrant septa on the cell wall, suggestive of impairment of the cell division machinery, was also observed.Entities:
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Year: 2008 PMID: 18378708 PMCID: PMC2415783 DOI: 10.1128/AAC.01410-07
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191