Literature DB >> 18378708

Daptomycin exerts bactericidal activity without lysis of Staphylococcus aureus.

Nicole Cotroneo1, Robert Harris, Nancy Perlmutter, Terry Beveridge, Jared A Silverman.   

Abstract

The ability of daptomycin to produce bactericidal activity against Staphylococcus aureus while causing negligible cell lysis has been demonstrated using electron microscopy and the membrane integrity probes calcein and ToPro3. The formation of aberrant septa on the cell wall, suggestive of impairment of the cell division machinery, was also observed.

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Year:  2008        PMID: 18378708      PMCID: PMC2415783          DOI: 10.1128/AAC.01410-07

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN: 0066-4804            Impact factor:   5.191


  10 in total

1.  CARE-LASS (calcein-release-assay), an improved fluorescence-based test system to measure cytotoxic T lymphocyte activity.

Authors:  R Lichtenfels; W E Biddison; H Schulz; A B Vogt; R Martin
Journal:  J Immunol Methods       Date:  1994-06-24       Impact factor: 2.303

2.  Scanning electronmicroscopy of Staphylococcus aureus and Enterococcus faecalis exposed to daptomycin.

Authors:  L J Wale; A P Shelton; D Greenwood
Journal:  J Med Microbiol       Date:  1989-09       Impact factor: 2.472

3.  Comparative in-vitro activity of LY146032 a new peptolide, with vancomycin and eight other agents against gram-positive organisms.

Authors:  C A Benson; F Beaudette; G Trenholm
Journal:  J Antimicrob Chemother       Date:  1987-08       Impact factor: 5.790

4.  Prevention of brain injury by the nonbacteriolytic antibiotic daptomycin in experimental pneumococcal meningitis.

Authors:  Denis Grandgirard; Christian Schürch; Philippe Cottagnoud; Stephen L Leib
Journal:  Antimicrob Agents Chemother       Date:  2007-03-19       Impact factor: 5.191

Review 5.  Minimizing the release of proinflammatory and toxic bacterial products within the host: a promising approach to improve outcome in life-threatening infections.

Authors:  Roland Nau; Helmut Eiffert
Journal:  FEMS Immunol Med Microbiol       Date:  2005-04-01

6.  The in vitro activity of daptomycin against 514 Gram-positive aerobic clinical isolates.

Authors:  A King; I Phillips
Journal:  J Antimicrob Chemother       Date:  2001-08       Impact factor: 5.790

7.  Multiparameter flow cytometric analysis of antibiotic effects on membrane potential, membrane permeability, and bacterial counts of Staphylococcus aureus and Micrococcus luteus.

Authors:  D J Novo; N G Perlmutter; R H Hunt; H M Shapiro
Journal:  Antimicrob Agents Chemother       Date:  2000-04       Impact factor: 5.191

8.  Fluorescence indicates a calcium-dependent interaction between the lipopeptide antibiotic LY146032 and phospholipid membranes.

Authors:  J H Lakey; M Ptak
Journal:  Biochemistry       Date:  1988-06-28       Impact factor: 3.162

9.  Bactericidal action of daptomycin against stationary-phase and nondividing Staphylococcus aureus cells.

Authors:  Carmela T M Mascio; Jeff D Alder; Jared A Silverman
Journal:  Antimicrob Agents Chemother       Date:  2007-10-08       Impact factor: 5.191

10.  Correlation of daptomycin bactericidal activity and membrane depolarization in Staphylococcus aureus.

Authors:  Jared A Silverman; Nancy G Perlmutter; Howard M Shapiro
Journal:  Antimicrob Agents Chemother       Date:  2003-08       Impact factor: 5.191

  10 in total
  48 in total

1.  Daptomycin-mediated reorganization of membrane architecture causes mislocalization of essential cell division proteins.

Authors:  Joe Pogliano; Nicolas Pogliano; Jared A Silverman
Journal:  J Bacteriol       Date:  2012-06-01       Impact factor: 3.490

2.  Novel daptomycin combinations against daptomycin-nonsusceptible methicillin-resistant Staphylococcus aureus in an in vitro model of simulated endocardial vegetations.

Authors:  Molly E Steed; Celine Vidaillac; Michael J Rybak
Journal:  Antimicrob Agents Chemother       Date:  2010-10-04       Impact factor: 5.191

3.  Regulation of mprF by antisense RNA restores daptomycin susceptibility to daptomycin-resistant isolates of Staphylococcus aureus.

Authors:  Aileen Rubio; Mary Conrad; Robert J Haselbeck; Kedar G C; Vickie Brown-Driver; John Finn; Jared A Silverman
Journal:  Antimicrob Agents Chemother       Date:  2010-10-25       Impact factor: 5.191

4.  Adjunctive daptomycin attenuates brain damage and hearing loss more efficiently than rifampin in infant rat pneumococcal meningitis.

Authors:  Denis Grandgirard; Melchior Burri; Philipp Agyeman; Stephen L Leib
Journal:  Antimicrob Agents Chemother       Date:  2012-05-29       Impact factor: 5.191

5.  Molecular State of the Membrane-Active Antibiotic Daptomycin.

Authors:  Ming-Tao Lee; Wei-Chin Hung; Meng-Hsuan Hsieh; Hsiung Chen; Yu-Yung Chang; Huey W Huang
Journal:  Biophys J       Date:  2017-07-11       Impact factor: 4.033

6.  Rapid killing of Acinetobacter baumannii by polymyxins is mediated by a hydroxyl radical death pathway.

Authors:  Timothy R Sampson; Xiang Liu; Max R Schroeder; Colleen S Kraft; Eileen M Burd; David S Weiss
Journal:  Antimicrob Agents Chemother       Date:  2012-08-20       Impact factor: 5.191

Review 7.  A current perspective on daptomycin for the clinical microbiologist.

Authors:  Romney M Humphries; Simon Pollett; George Sakoulas
Journal:  Clin Microbiol Rev       Date:  2013-10       Impact factor: 26.132

8.  Evaluation of the novel combination of high-dose daptomycin plus trimethoprim-sulfamethoxazole against daptomycin-nonsusceptible methicillin-resistant Staphylococcus aureus using an in vitro pharmacokinetic/pharmacodynamic model of simulated endocardial vegetations.

Authors:  Molly E Steed; Brian J Werth; Cortney E Ireland; Michael J Rybak
Journal:  Antimicrob Agents Chemother       Date:  2012-08-20       Impact factor: 5.191

9.  The phosphoenolpyruvate:sugar phosphotransferase system is involved in sensitivity to the glucosylated bacteriocin sublancin.

Authors:  C V Garcia De Gonzalo; E L Denham; R A T Mars; J Stülke; W A van der Donk; J M van Dijl
Journal:  Antimicrob Agents Chemother       Date:  2015-08-17       Impact factor: 5.191

10.  The efficacy and safety of daptomycin vs. vancomycin for the treatment of cellulitis and erysipelas.

Authors:  P E Pertel; B I Eisenstein; A S Link; B Donfrid; E J A Biermann; P Bernardo; W J Martone
Journal:  Int J Clin Pract       Date:  2009-03       Impact factor: 2.503

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