Literature DB >> 18378196

Numerical simulations for detailed airflow dynamics in a human nasal cavity.

Jian Wen1, Kiao Inthavong, Jiyuan Tu, Simin Wang.   

Abstract

Nasal physiology is dependent on the physical structure of the nose. Individual aspects of the nasal cavity such as the geometry and flow rate collectively affect nasal function such as the filtration of foreign particles by bringing inspired air into contact with mucous-coated walls, humidifying and warming the air before it enters the lungs and the sense of smell. To better understand the physiology of the nose, this study makes use of CFD methods and post-processing techniques to present flow patterns between the left and right nasal cavities and compared the results with experimental and numerical data that are available in literature. The CFD simulation adopted a laminar steady flow for flow rates of 7.5 L/min and 15 L/min. General agreement of gross flow features were found that included high velocities in the constrictive nasal valve area region, high flow close to the septum walls, and vortex formations posterior to the nasal valve and olfactory regions. The differences in the left and right cavities were explored and the effects it had on the flow field were discussed especially in the nasal valve and middle turbinate regions. Geometrical differences were also compared with available models.

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Year:  2008        PMID: 18378196     DOI: 10.1016/j.resp.2008.01.012

Source DB:  PubMed          Journal:  Respir Physiol Neurobiol        ISSN: 1569-9048            Impact factor:   1.931


  20 in total

1.  First Steps to Develop and Validate a CFPD Model in Order to Support the Design of Nose-to-Brain Delivered Biopharmaceuticals.

Authors:  Lucas Engelhardt; Martina Röhm; Chrystelle Mavoungou; Katharina Schindowski; Annette Schafmeister; Ulrich Simon
Journal:  Pharm Res       Date:  2016-02-17       Impact factor: 4.200

2.  Numerical simulation of normal nasal cavity airflow in Chinese adult: a computational flow dynamics model.

Authors:  Jie Tan; Demin Han; Jie Wang; Ting Liu; Tong Wang; Hongrui Zang; Yunchuan Li; Xiangdong Wang
Journal:  Eur Arch Otorhinolaryngol       Date:  2011-09-22       Impact factor: 2.503

3.  On locating the obstruction in the upper airway via numerical simulation.

Authors:  Yong Wang; S Elghobashi
Journal:  Respir Physiol Neurobiol       Date:  2013-12-31       Impact factor: 1.931

4.  Computational fluid dynamics: a suitable assessment tool for demonstrating the antiobstructive effect of drugs in the therapy of allergic rhinitis.

Authors:  N Achilles; N Pasch; A Lintermann; W Schröder; R Mösges
Journal:  Acta Otorhinolaryngol Ital       Date:  2013-02       Impact factor: 2.124

5.  New CFD tools to evaluate nasal airflow.

Authors:  M A Burgos; E Sanmiguel-Rojas; C Del Pino; M A Sevilla-García; F Esteban-Ortega
Journal:  Eur Arch Otorhinolaryngol       Date:  2017-05-25       Impact factor: 2.503

6.  Numerical simulation for the upper airway flow characteristics of Chinese patients with OSAHS using CFD models.

Authors:  Jie Tan; Jianmin Huang; Jianguo Yang; Desheng Wang; Jianzhi Liu; Jingbo Liu; Shuchun Lin; Chen Li; Haichun Lai; Hongyu Zhu; Xiaohua Hu; Dongxu Chen; Longxiang Zheng
Journal:  Eur Arch Otorhinolaryngol       Date:  2013-02-03       Impact factor: 2.503

7.  Correlation of regional deposition dosage for inhaled nanoparticles in human and rat olfactory.

Authors:  Lin Tian; Yidan Shang; Rui Chen; Ru Bai; Chunying Chen; Kiao Inthavong; Jiyuan Tu
Journal:  Part Fibre Toxicol       Date:  2019-01-25       Impact factor: 9.400

8.  Role of nasal vestibule morphological variations on olfactory airflow dynamics.

Authors:  Ryan M Sicard; Dennis O Frank-Ito
Journal:  Clin Biomech (Bristol, Avon)       Date:  2021-01-27       Impact factor: 2.063

9.  Standardization of Malaysian adult female nasal cavity.

Authors:  Chih Fang Lee; Mohd Zulkifly Abdullah; Kamarul Arifin Ahmad; Ibrahim Lutfi Shuaib
Journal:  Comput Math Methods Med       Date:  2013-06-15       Impact factor: 2.238

10.  Impacts of fluid dynamics simulation in study of nasal airflow physiology and pathophysiology in realistic human three-dimensional nose models.

Authors:  De Yun Wang; Heow Peuh Lee; Bruce R Gordon
Journal:  Clin Exp Otorhinolaryngol       Date:  2012-11-13       Impact factor: 3.372

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