Literature DB >> 18377262

Bilateral malignant melanoma metastases to the internal auditory canal/cerebellopontine angle: surgical management and preservation of function.

Venelin M Gerganov1, Nirjhar Hore, Christian Herold, Karsten Wrede, Alexandru C Stan, Amir Samii, Madjid Samii.   

Abstract

Although intracranial metastases of malignant melanomas are common, localization at the cerebellopontine angle (CPA) or in the internal auditory canal (IAC) is rare, and bilateral presentation especially so. We present the case of a 46-year-old Caucasian woman with bilateral IAC/CPA lesions and a prior history of malignant melanoma on the right leg. During preoperative investigations, the presence of the bilateral IAC/CPA lesions along with several radiologically identified lesions along the neural axis led to the suspicion that she had neurofibromatosis Type 2 despite her history of malignant melanoma and the lack of characteristic skin lesions and family history. Histopathological analysis of the resected lesion confirmed the intraoperative diagnosis of bilateral CPA malignant melanoma metastases. Surgical removal of the tumors via the retrosigmoid approach with preservation of normal bilateral facial nerve function and unilateral serviceable hearing, combined with control of the systemic disease, provided this patient with a near-normal quality of life for at least 42 months after the initial diagnosis of melanoma.

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Mesh:

Year:  2008        PMID: 18377262     DOI: 10.3171/JNS/2008/108/4/0803

Source DB:  PubMed          Journal:  J Neurosurg        ISSN: 0022-3085            Impact factor:   5.115


  6 in total

1.  Bilateral malignant metastases to the internal auditory canal: radiosurgical management.

Authors:  Marcos Dellaretti; Eduardo K Tagawa; Julio Leonardo Barbosa Pereira; Mariana Pedrini; Baltazar Leão Reis; Atos Alves de Sousa
Journal:  J Radiosurg SBRT       Date:  2011

2.  Imaging case of the month: Bilateral internal auditory canal melanoma.

Authors:  Rachel E Roditi; Priya Kesarwani; Eric M Barker; Gabrielle A Yeaney; Kevin A Walter; Benjamin T Crane
Journal:  Otol Neurotol       Date:  2012-12       Impact factor: 2.311

3.  The 'full-blown' MRI of sudden hearing loss: 3D FLAIR in a patient with bilateral metastases in the internal auditory canals.

Authors:  Giorgio Conte; Federica Di Berardino; Diego Zanetti; Sabrina Avignone; Clara Sina; Elisabetta Iofrida; Fabio Triulzi
Journal:  Neuroradiol J       Date:  2017-10-19

Review 4.  Non-schwannomatosis lesions of the internal acoustic meatus-a diagnostic challenge and management: a series report of nine cases.

Authors:  Luis Fernando Moura da Silva; Viviane Aline Buffon; Maurício Coelho Neto; Ricardo Ramina
Journal:  Neurosurg Rev       Date:  2015-05-10       Impact factor: 3.042

5.  Melanoma Mimicking Malignant Peripheral Nerve Sheath Tumor with Spread to the Cerebellopontine Angle: Utility of Next-Generation Sequencing in Diagnosis.

Authors:  Katie Fox Hanson; Paul Birinyi; Ronald Walker; Constantine Raptis; Rebecca Chernock; Jeroen Coppens; Katherine E Schwetye
Journal:  Case Rep Pathol       Date:  2018-06-28

6.  Bilateral internal auditory canal gangliogliomas mimicking neurofibromatosis Type II.

Authors:  Kristopher G Hooten; Seth F Oliveria; Saeed S Sadrameli; Shashank Gandhi; Anthony T Yachnis; Stephen B Lewis
Journal:  Surg Neurol Int       Date:  2016-04-13
  6 in total

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