An optical high-pressure cell for transient grating measurements of biological substance with a high reproducibility.

We describe a high-pressure optical cell that can be used for time-resolved transient grating measurements to determine the thermodynamic properties of transient species under high pressure. This high-pressure cell enables us to compare the grating signal intensities of different samples quantitatively. Using this high-pressure cell with an inner sample cell, one can measure various thermodynamic properties of a biological substance in time domain. The stability and reproducibility of this apparatus are described.