| Literature DB >> 18376828 |
Qing-Gang Wang1, Xian-Ming Deng, Ben-Hu Zhu, Long-Wu Ye, Xiu-Li Sun, Chuan-Ying Li, Chun-Yin Zhu, Qi Shen, Yong Tang.
Abstract
A highly efficient diastereoselective synthesis of cyclohexadiene epoxide derivatives with a multi-stereocenter has been developed via a tandem ylide Michael addition/epoxidation. By employing a chiral sulfonium ylide, up to 96% ee can be achieved in good yields.Entities:
Year: 2008 PMID： 18376828 DOI： 10.1021/ja800747m
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419