Literature DB >> 18376511

Start low, go slow, but don't go this way yet.

Brian Bressler, Robert Enns.   

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Year:  2008        PMID: 18376511      PMCID: PMC2659128          DOI: 10.1155/2008/280349

Source DB:  PubMed          Journal:  Can J Gastroenterol        ISSN: 0835-7900            Impact factor:   3.522


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  28 in total

Review 1.  Use of laboratory testing to guide 6-mercaptopurine/azathioprine therapy.

Authors:  Gary R Lichtenstein
Journal:  Gastroenterology       Date:  2004-11       Impact factor: 22.682

2.  Toxicity of 6-thioguanine: no hepatotoxicity in a series of IBD patients treated with long-term, low dose 6-thioguanine. Some evidence for dose or metabolite level dependent effects?

Authors:  L P L Gilissen; L J J Derijks; A Driessen; L P Bos; P M Hooymans; R W Stockbrügger; L G J B Engels
Journal:  Dig Liver Dis       Date:  2006-12-26       Impact factor: 4.088

3.  Therapeutic drug monitoring of azathioprine and 6-mercaptopurine metabolites in Crohn disease.

Authors:  J Belaiche; J P Desager; Y Horsmans; E Louis
Journal:  Scand J Gastroenterol       Date:  2001-01       Impact factor: 2.423

4.  On tolerability and safety of a maintenance treatment with 6-thioguanine in azathioprine or 6-mercaptopurine intolerant IBD patients.

Authors:  Nanne-K-H de Boer; Luc-J-J Derijks; Lennard-P-L Gilissen; Daniel-W Hommes; Leopold-G-J-B Engels; Sybrand-Y de-Boer; Gijsbertus den Hartog; Piet-M Hooymans; Anja-B-U Mäkelburg; Barend-D Westerveld; Anton-H-J Naber; Chris-J-J Mulder; Dirk-J de Jong
Journal:  World J Gastroenterol       Date:  2005-09-21       Impact factor: 5.742

5.  The utility of 6-thioguanine metabolite levels in managing patients with inflammatory bowel disease.

Authors:  Benjamin A Goldenberg; Patricia Rawsthorne; Charles N Bernstein
Journal:  Am J Gastroenterol       Date:  2004-09       Impact factor: 10.864

6.  Thiopurine methyltransferase activity influences clinical response to azathioprine in inflammatory bowel disease.

Authors:  Carmen Cuffari; Themistocles Dassopoulos; Lisa Turnbough; Richard E Thompson; Theodore M Bayless
Journal:  Clin Gastroenterol Hepatol       Date:  2004-05       Impact factor: 11.382

7.  Cost-effectiveness of thiopurine methyltransferase genotype screening in patients about to commence azathioprine therapy for treatment of inflammatory bowel disease.

Authors:  J Winter; A Walker; D Shapiro; D Gaffney; R J Spooner; P R Mills
Journal:  Aliment Pharmacol Ther       Date:  2004-09-15       Impact factor: 8.171

Review 8.  Azathioprine, 6-mercaptopurine in inflammatory bowel disease: pharmacology, efficacy, and safety.

Authors:  Marla C Dubinsky
Journal:  Clin Gastroenterol Hepatol       Date:  2004-09       Impact factor: 11.382

9.  Individualizing therapy with 6-mercaptopurine and 6-thioguanine related to the thiopurine methyltransferase genetic polymorphism.

Authors:  L Lennard; J S Lilleyman
Journal:  Ther Drug Monit       Date:  1996-08       Impact factor: 3.681

10.  6-Thioguanine seems promising in azathioprine- or 6-mercaptopurine-intolerant inflammatory bowel disease patients: a short-term safety assessment.

Authors:  Luc J J Derijks; Dirk J de Jong; Lennard P L Gilissen; Leopold G J B Engels; Piet M Hooymans; Jan B M J Jansen; Chris J J Mulder
Journal:  Eur J Gastroenterol Hepatol       Date:  2003-01       Impact factor: 2.566

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