Literature DB >> 18376168

Injury severity and causes of death from Operation Iraqi Freedom and Operation Enduring Freedom: 2003-2004 versus 2006.

Joseph F Kelly1, Amber E Ritenour, Daniel F McLaughlin, Karen A Bagg, Amy N Apodaca, Craig T Mallak, Lisa Pearse, Mary M Lawnick, Howard R Champion, Charles E Wade, John B Holcomb.   

Abstract

BACKGROUND: The opinion that injuries sustained in Iraq and Afghanistan have increased in severity is widely held by clinicians who have deployed multiple times. To continuously improve combat casualty care, the Department of Defense has enacted numerous evidence-based policies and clinical practice guidelines. We hypothesized that the severity of wounds has increased over time. Furthermore, we examined cause of death looking for opportunities of improvement for research and training.
METHODS: Autopsies of the earliest combat deaths from Iraq and Afghanistan and the latest deaths of 2006 were analyzed to assess changes in injury severity and causes of death. Fatalities were classified as nonsurvivable (NS) or potentially survivable (PS). PS deaths were then reviewed in depth to analyze mechanism and cause.
RESULTS: There were 486 cases from March 2003 to April 2004 (group 1) and 496 from June 2006 to December 2006 (group 2) that met inclusion criteria. Of the PS fatalities (group 1: 93 and group 2: 139), the injury severity score was lower in the first group (27 +/- 14 vs. 37 +/- 16, p < 0.001), and had a lower number of abbreviated injury scores >or=4 (1.1 +/- 0.79 vs. 1.5 +/- 0.83 per person, p < 0.001). The main cause of death in the PS fatalities was truncal hemorrhage (51% vs. 49%, p = NS). Deaths per month between groups doubled (35 vs. 71), whereas the case fatality rates between the two time periods were equivalent (11.0 vs. 9.8, p = NS). DISCUSSION: In the time periods of the war studied, deaths per month has doubled, with increases in both injury severity and number of wounds per casualty. Truncal hemorrhage is the leading cause of potentially survivable deaths. Arguably, the success of the medical improvements during this war has served to maintain the lowest case fatality rate on record.

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Year:  2008        PMID: 18376168     DOI: 10.1097/TA.0b013e318160b9fb

Source DB:  PubMed          Journal:  J Trauma        ISSN: 0022-5282


  82 in total

Review 1.  Tactical combat casualty care in the Canadian Forces: lessons learned from the Afghan war.

Authors:  Erin Savage; Colleen Forestier; Nicholas Withers; Homer Tien; Dylan Pannell
Journal:  Can J Surg       Date:  2011-12       Impact factor: 2.089

2.  Cause and timing of death in massively transfused trauma patients.

Authors:  Michael W Cripps; Matthew E Kutcher; Aaron Daley; Ryan C McCreery; Molly D Greenberg; Leslie M Cachola; Brittney J Redick; Mary F Nelson; Mitchell Jay Cohen
Journal:  J Trauma Acute Care Surg       Date:  2013-08       Impact factor: 3.313

3.  Characteristics and treatment of vascular injuries: a review of 387 cases at a Chinese center.

Authors:  Zhui Li; Liang Zhao; Kaizhen Wang; Jun Cheng; Yu Zhao; Wei Ren
Journal:  Int J Clin Exp Med       Date:  2014-12-15

4.  A high fresh frozen plasma: packed red blood cell transfusion ratio decreases mortality in all massively transfused trauma patients regardless of admission international normalized ratio.

Authors:  Lisa M Brown; Seppo O Aro; Mitchell J Cohen; J B Holcomb; C E Wade; K J Brasel; G Vercruysse; J MacLeod; R P Dutton; J R Hess; J C Duchesne; N E McSwain; P Muskat; J Johannigamn; H M Cryer; A Tillou; J F Pittet; P Knudson; M A De Moya; M A Schreiber; B Tieu; S Brundage; L M Napolitano; M Brunsvold; K C Sihler; G Beilman; A B Peitzman; M S Zenait; J Sperry; L Alarcon; M A Croce; J P Minei; R Kozar; E A Gonzalez; R M Stewart; S M Cohn; J E Mickalek; E M Bulger; B A Cotton; T C Nunez; R Ivatury; J W Meredith; P Miller; G J Pomper; B Marin
Journal:  J Trauma       Date:  2011-08

5.  Clot Formation Is Associated With Fibrinogen and Platelet Forces in a Cohort of Severely Injured Emergency Department Trauma Patients.

Authors:  Nathan J White; Jason C Newton; Erika J Martin; Bassem M Mohammed; Daniel Contaifer; Jessica L Bostic; Gretchen M Brophy; Bruce D Spiess; Anthony E Pusateri; Kevin R Ward; Donald F Brophy
Journal:  Shock       Date:  2015-08       Impact factor: 3.454

6.  Comparison of the topical haemostatic efficacy of nano-micro particles of clinoptilolite and kaolin in a rat model of haemorrhagic injury.

Authors:  A Bayır; M Eryılmaz; M Demirbilek; E B Denkbaş; I Arzıman; M Durusu
Journal:  Eur J Trauma Emerg Surg       Date:  2015-03-14       Impact factor: 3.693

7.  Pharmacologic resuscitation promotes survival and attenuates hemorrhage-induced activation of extracellular signal-regulated kinase 1/2.

Authors:  Eugene Y Fukudome; Ashley R Kochanek; Yongqing Li; Eleanor J Smith; Baoling Liu; Tareq Kheirbek; Jennifer Lu; Kyuseok Kim; Kristopher Hamwi; George C Velmahos; Hasan B Alam
Journal:  J Surg Res       Date:  2010-05-07       Impact factor: 2.192

8.  A hydrogel sealant for the treatment of severe hepatic and aortic trauma with a dissolution feature for post-emergent care.

Authors:  Marlena D Konieczynska; Juan C Villa-Camacho; Cynthia Ghobril; Miguel Perez-Viloria; William A Blessing; Ara Nazarian; Edward K Rodriguez; Mark W Grinstaff
Journal:  Mater Horiz       Date:  2016-12-23       Impact factor: 13.266

Review 9.  Traumatic brain injury and aeromedical evacuation: when is the brain fit to fly?

Authors:  Michael D Goodman; Amy T Makley; Alex B Lentsch; Stephen L Barnes; Gina R Dorlac; Warren C Dorlac; Jay A Johannigman; Timothy A Pritts
Journal:  J Surg Res       Date:  2009-08-26       Impact factor: 2.192

10.  Pragmatic Randomized Optimal Platelet and Plasma Ratios (PROPPR) Trial: design, rationale and implementation.

Authors:  Sarah Baraniuk; Barbara C Tilley; Deborah J del Junco; Erin E Fox; Gerald van Belle; Charles E Wade; Jeanette M Podbielski; Angela M Beeler; John R Hess; Eileen M Bulger; Martin A Schreiber; Kenji Inaba; Timothy C Fabian; Jeffrey D Kerby; Mitchell Jay Cohen; Christopher N Miller; Sandro Rizoli; Thomas M Scalea; Terence O'Keeffe; Karen J Brasel; Bryan A Cotton; Peter Muskat; John B Holcomb
Journal:  Injury       Date:  2014-06-10       Impact factor: 2.586

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